Time course of immune cell population changes post injury.

<p>(A) Percent of total for each immune population identified through scRNA-seq, determined as a proportion of all immune cells sequenced. Colors based on immune cluster identities denoted in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0312587#pone.0312587.g00...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Jillian L. McCool (13174542) (author)
مؤلفون آخرون:	Aimy Sebastian (823355) (author), Nicholas R. Hum (12563075) (author), Stephen P. Wilson (13174545) (author), Oscar A. Davalos (19447159) (author), Deepa K. Murugesh (4621030) (author), Beheshta Amiri (13174548) (author), Cesar Morfin (20501089) (author), Blaine A. Christiansen (13174551) (author), Gabriela G. Loots (12563087) (author)
منشور في:	2025
الموضوعات:	Biophysics Biochemistry Microbiology Cell Biology Physiology Pharmacology Biotechnology Evolutionary Biology Ecology Immunology Developmental Biology Hematology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified sup >+</ sup rest spontaneously resolve immune cell populations identified significant differences div >< p cell rna sequencing anterior cruciate ligament myeloid cell activation inflammatory signaling seen apoptotic cells induced murine knee joint joint injuries progress mrl injured joints potent myeloid inflammatory response induced fluctuations synovial joints traumatic osteoarthritis transcriptional shifts synovial tissue susceptible c57bl stabilizing tissues significantly contrasted resistant mrl receptor involved medial meniscus macrophage subpopulations macrophage accumulation found enriched enhanced capacity driven anti data suggest connective tissues clearing debris articular fractures
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الوصف
الملخص:	<p>(A) Percent of total for each immune population identified through scRNA-seq, determined as a proportion of all immune cells sequenced. Colors based on immune cluster identities denoted in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0312587#pone.0312587.g001" target="_blank">Fig 1D</a>. (B) Flow cytometry gating strategy for <i>Ly6c+</i> monocytes/macrophages (Mono/Mac) and neutrophil populations. (C) Trend of <i>Ly6c</i><sup><i>+</i></sup> monocytes and macrophages after injury. (D) Trend of Ly6g<sup>+</sup> neutrophils after injury.</p>

Time course of immune cell population changes post injury.

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