Sample size by phenotype and ancestry group.

مواد مشابهة

• Significantly enriched Gene Ontology (GO) terms among the 512 genes showing significant results in the all ancestry TWAS. Enrichment analyses were conducted using the multi-query in g:Profiler [16]. Columns include source, term name, GO id, and adjusted p-values across each phenotype definition. P-values were adjusted to maintain an experiment-wide type 1 error rate of 0.05 using the g:SCS algorithm which accounts for the dependent structure of functionally annotated gene sets.
  حسب: Jenna C. Carlson (3950024)
  منشور في: (2025)
• Results from genome-wide all ancestry meta-analysis for each independent lead variant demonstrating genome-wide significance (p < 5e-8) in at least one phenotype. Columns include Chromosome (Chr), position (hg38), reference and alternate (effect) alleles (Ref/Alt), rsID, candidate gene (either the gene nearest the variant or a previously implicated risk gene), direction of effect (Dir) on any cleft for POFC1, POFC2, and GENEVA OFC, respectively (? indicates variant was not present in that study), and p-values and from meta-analysis across each phenotype definition.
  حسب: Jenna C. Carlson (3950024)
  منشور في: (2025)
• Gene expression patterns from single-cell RNA sequencing of human craniofacial tissue [15] of four genes intersecting all ancestry GWAS and TWAS (<i>CALD1</i>, <i>ESRP1</i>, <i>NTN1</i>, and <i>TANC2</i>) (A) grouped by cell type and (B) grouped by Carnegie Stage (CS).
  حسب: Jenna C. Carlson (3950024)
  منشور في: (2025)
• Venn Diagram showing the number of genes significant in TWAS results for the five cleft types.
  حسب: Jenna C. Carlson (3950024)
  منشور في: (2025)
• Integrated genomic analysis of the association at 16p13.3 with cleft lip with or without cleft palate (CL/P).
  حسب: Jenna C. Carlson (3950024)
  منشور في: (2025)