Gene sequences.

Gene sequences.

<div><p>Cancer is one of the major diseases that threaten human life and causes death for many people worldwide. Some alkaloids derived from plants show promising potential for cancer treatment. Solanaceae family is of these plants that have promising alkaloid. In this study alkaloid pro...

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Xehetasun bibliografikoak
Egile nagusia:	Abdulkarim Dakah (22110558) (author)
Beste egile batzuk:	Iyad Musallam (22110561) (author), Raida Wajih Khalil (22110564) (author)
Argitaratua:	2025
Gaiak:	Biochemistry Cell Biology Genetics Molecular Biology Pharmacology Ecology Immunology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified untreated mcf7 cells threaten human life many people worldwide cdk1 gene expression solanum elaeagnifolium </ optimal callus growth div >< p study alkaloid production ms analysis showed elaeagnifolium </ alkaloid production cdk1 levels analysis revealed promising alkaloid predominant alkaloid yeast extract solanaceae family related genes promising candidate mtt assay media enriched major diseases lower efficacy important alkaloids extracts treatment effective response causes death callus medium callus extracts callus cultures balanced concentration anticancer therapy anticancer properties alkaloids derived 7 %) 50 µl
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Antzeko izenburuak

Gene expression of MCF7 breast cancer cells treated with <i><i>solanum elaeagnifolium</i></i> callus extracts at 12 and 24 h.
nork: Abdulkarim Dakah (22110558)
Argitaratua: (2025)

Anticancer activities of <i><i>Solanum elaeagnifolium</i></i> alkaloids extracts on death of MCF7 Breast Cancer Cell Line after 24 h of treatment (IC<sub>50</sub> ± SE).
nork: Abdulkarim Dakah (22110558)
Argitaratua: (2025)

Alkaloid componentsidentified in <i><i>Solanum elaeagnifolium</i></i> leaf and callus cultures (CGM1–CGM4) by Liquid -chromatography–mass spectrometry.
nork: Abdulkarim Dakah (22110558)
Argitaratua: (2025)

Effect of the different ratio of growth regulator (BAP:2,4-D), with, and without NaCl and yeast extract supplemented to MS medium on callus diameter, color and softens of Solanum elaeagnifolium Cav.
nork: Abdulkarim Dakah (22110558)
Argitaratua: (2025)

The different treatments of growth regulators, NaCl and yeast extract supplemented to MS medium to test theireffect on alkaloid production.
nork: Abdulkarim Dakah (22110558)
Argitaratua: (2025)

Gene Expression (RT-PCR).
nork: Abdulkarim Dakah (22110558)
Argitaratua: (2025)

Chromatogram profiles of <i>Solanum elaeagnifolium.</i>
nork: Abdulkarim Dakah (22110558)
Argitaratua: (2025)

Callus induction.
nork: Abdulkarim Dakah (22110558)
Argitaratua: (2025)

Solanum elaeagnifolium.
nork: Abdulkarim Dakah (22110558)
Argitaratua: (2025)

Analysis of variance results for the effect of drought stress treatment and tryptophan amino acid on the physiological indices of the periwinkle plant.
nork: Farshid Yousefi (22403640)
Argitaratua: (2025)

Results of the analysis of variance (ANOVA) regarding the effects of drought stress treatment and the amino acid tryptophan at various time intervals on the alkaloids vincristine and vinblastine in the periwinkle plant.
nork: Farshid Yousefi (22403640)
Argitaratua: (2025)

Name, sequence, annealing temperature, accession number and amplified fragment of primers.
nork: Farshid Yousefi (22403640)
Argitaratua: (2025)

Comparative analysis of drought stress treatment response with the amino acid tryptophan concerning total plant dry weight trait.
nork: Farshid Yousefi (22403640)
Argitaratua: (2025)

Comparison of the mean response of drought stress treatments (100 and 40% of field capacity) with different concentrations of the amino acid tryptophan (0 and 250 mg/L) at various times (24, 48, 72 and 168 hours) in terms of phenol (A) and flavonoid (B) traits.
nork: Farshid Yousefi (22403640)
Argitaratua: (2025)

Comparison of the response of drought stress treatments (100 and 40% of field capacity) to different amino acids tryptophan (0 and 250 mg/L) at different times (72 and 168 hours), based on vincristine (A) and vinblastine (B) traits.
nork: Farshid Yousefi (22403640)
Argitaratua: (2025)

The graph of changes in the relative expression of A, B, C and D, respectively, <i>Sls</i>, <i>Str</i>, <i>Dat</i> and <i>Prx</i> gene over time (24, 48, 72 and 168 hours).
nork: Farshid Yousefi (22403640)
Argitaratua: (2025)

The graph of changes in the relative expression of A, B and C, respectively, <i>Cm</i>, <i>As</i> and <i>Tdc</i> gene over time (24, 48, 72 and 168 hours).
nork: Farshid Yousefi (22403640)
Argitaratua: (2025)

Seedlings of <i>C. roseus.</i>
nork: Farshid Yousefi (22403640)
Argitaratua: (2025)

Schematic view of the poplin related to the study stages.
nork: Farshid Yousefi (22403640)
Argitaratua: (2025)

Synthesis pathway of terpenoid indole alkaloids in leaf tissue [17]. TIAs pathway consists of three indole pathways, terpenoid pathway and alkaloid pathway, the final products of terpenoid and indole pathways enter the alkaloid pathway with the activity of STR enzyme and make compounds of indole terpenoid alkaloids in leaf and root tissues.
nork: Farshid Yousefi (22403640)
Argitaratua: (2025)

Dietary psychoactive xenobiotics: an updated review on food contamination with ergot, tropane and opium alkaloids and their toxicological effects
nork: Inês Margarido Martins (21605722)
Argitaratua: (2025)

Genotoxic Mechanisms of Erythrophleum suaveolens Stem Bark Extracts and Fractions in MCF-7 Breast Cancer Cells via Mitochondrial and Non-Mitochondrial Pathways
nork: Lateef Sulaimon (21706283)
Argitaratua: (2025)

Data Sheet 1_Synthesis, pharmacokinetic studies, and metabolite analysis of meridianin C in rats using a validated ultra high performance liquid chromatography-tandem mass spectrometry method.docx
nork: Liangyu Xu (21467108)
Argitaratua: (2025)

Data Sheet 1_Alkaloid biosynthesis in medicinal crop kratom (Mitragyna speciosa) varies with postharvest, genetic, and seasonal factors.docx
nork: Mengzi Zhang (1416139)
Argitaratua: (2025)

Collective Synthesis and PCSK9 Inhibitory Activities of Pavine and Isopavine Alkaloids
nork: Xiaohui Geng (7916219)
Argitaratua: (2025)

Table 1_A fatal intractable ventricular fibrillation triggered by improper use of Xiaozhong Jiuwei Powder: integrated LC-MS chemical profiling unveils the cardiotoxic culprits.docx
nork: Halidan Abudu (22500023)
Argitaratua: (2025)

<sup>1</sup>H and <sup>13</sup>C NMR data for compounds 1–3 (in CDCl<sub>3</sub>).
nork: Nicolas Fabre (707117)
Argitaratua: (2025)

Proposed biosynthetic pathways of guaipyridine (A, according to [26]), cadinapyridine (B, according to [23]) sesquiterpene alkaloids, and for compound 2 (C).
nork: Nicolas Fabre (707117)
Argitaratua: (2025)

<sup>1</sup>HNMR multiplicities of H-7, H-10 and H-11 for cadinapyridines 1-3.
nork: Nicolas Fabre (707117)
Argitaratua: (2025)

Molecular view of compound 1 based on single X-ray crystallographic analysis.
nork: Nicolas Fabre (707117)
Argitaratua: (2025)

Key HMBC and COSY correlations of 1.
nork: Nicolas Fabre (707117)
Argitaratua: (2025)

Structures of cadinapyridines 1-3.
nork: Nicolas Fabre (707117)
Argitaratua: (2025)

Table 2_Indirect somatic embryogenesis of Agave maximiliana Baker.docx
nork: Lourdes Delgado-Aceves (22135591)
Argitaratua: (2025)

Table 1_Indirect somatic embryogenesis of Agave maximiliana Baker.docx
nork: Lourdes Delgado-Aceves (22135591)
Argitaratua: (2025)

Image 1_Metabolic profiling and pharmacological evaluation of alkaloids in three Murraya species.jpeg
nork: Huaxi Huang (8448459)
Argitaratua: (2025)

Table 1_Metabolic profiling and pharmacological evaluation of alkaloids in three Murraya species.xlsx
nork: Huaxi Huang (8448459)
Argitaratua: (2025)

Regeneration and transformation dataset for <i>Eucalyptus </i> sp.7
nork: Thembela Lulane (22546154)
Argitaratua: (2025)

Data Sheet 1_Natural metabolites used in traditional Chinese medicine for cardiovascular diseases: pharmacological mechanisms, evidence, and future directions.pdf
nork: Xinyu Liu (34266)
Argitaratua: (2025)

Supplementary file 1_Synergistic anticancer effects of camptothecin and sotorasib in KRAS-mutated pancreatic ductal adenocarcinoma.docx
nork: Prasanna Srinivasan Ramalingam (16362915)
Argitaratua: (2025)

Supplementary file 2_Synergistic anticancer effects of camptothecin and sotorasib in KRAS-mutated pancreatic ductal adenocarcinoma.xlsx
nork: Prasanna Srinivasan Ramalingam (16362915)
Argitaratua: (2025)