Supplementary Table S7 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
<p>Table S7 shows (a) reproducible peaks and (b) GO analysis of ELAVL1-bound transcripts identified in the eCLIP-sequencing data set. The negatively enriched (c) and positively-enriched (d) gene sets identified by GSEA of ELAVL1-bound and differentially expressed transcripts from the RN2c RNA-...
محفوظ في:
| المؤلف الرئيسي: | |
|---|---|
| مؤلفون آخرون: | , , , , , , , , , , , , , , , , , , , , , |
| منشور في: |
2025
|
| الموضوعات: | |
| الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|
| _version_ | 1849927640286232576 |
|---|---|
| author | Ana Vujovic (15207479) |
| author2 | Laura de Rooij (15207482) Ava Keyvani Chahi (15207485) He Tian Chen (15207488) Brian A. Yee (15207491) Sampath K. Loganathan (15121740) Lina Liu (15207494) Derek C.H. Chan (15207497) Amanda Tajik (15207500) Emily Tsao (15207503) Steven Moreira (14937143) Pratik Joshi (15207506) Joshua Xu (15207509) Nicholas Wong (15207512) Zaldy Balde (15207515) Soheil Jahangiri (15207518) Sasan Zandi (15207521) Stefan Aigner (15207524) John E. Dick (14937554) Mark D. Minden (14961936) Daniel Schramek (15121764) Gene W. Yeo (15207527) Kristin J. Hope (15207530) |
| author2_role | author author author author author author author author author author author author author author author author author author author author author author |
| author_facet | Ana Vujovic (15207479) Laura de Rooij (15207482) Ava Keyvani Chahi (15207485) He Tian Chen (15207488) Brian A. Yee (15207491) Sampath K. Loganathan (15121740) Lina Liu (15207494) Derek C.H. Chan (15207497) Amanda Tajik (15207500) Emily Tsao (15207503) Steven Moreira (14937143) Pratik Joshi (15207506) Joshua Xu (15207509) Nicholas Wong (15207512) Zaldy Balde (15207515) Soheil Jahangiri (15207518) Sasan Zandi (15207521) Stefan Aigner (15207524) John E. Dick (14937554) Mark D. Minden (14961936) Daniel Schramek (15121764) Gene W. Yeo (15207527) Kristin J. Hope (15207530) |
| author_role | author |
| dc.creator.none.fl_str_mv | Ana Vujovic (15207479) Laura de Rooij (15207482) Ava Keyvani Chahi (15207485) He Tian Chen (15207488) Brian A. Yee (15207491) Sampath K. Loganathan (15121740) Lina Liu (15207494) Derek C.H. Chan (15207497) Amanda Tajik (15207500) Emily Tsao (15207503) Steven Moreira (14937143) Pratik Joshi (15207506) Joshua Xu (15207509) Nicholas Wong (15207512) Zaldy Balde (15207515) Soheil Jahangiri (15207518) Sasan Zandi (15207521) Stefan Aigner (15207524) John E. Dick (14937554) Mark D. Minden (14961936) Daniel Schramek (15121764) Gene W. Yeo (15207527) Kristin J. Hope (15207530) |
| dc.date.none.fl_str_mv | 2025-11-24T22:02:24Z |
| dc.identifier.none.fl_str_mv | 10.1158/2643-3230.30698685 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/dataset/Supplementary_Table_S7_from_i_In_Vivo_i_Screening_Unveils_Pervasive_RNA-Binding_Protein_Dependencies_in_Leukemic_Stem_Cells_and_Identifies_ELAVL1_as_a_Therapeutic_Target/30698685 |
| dc.rights.none.fl_str_mv | CC BY info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Cancer Cancer Biology Molecular and Cellular Biology Therapeutic Research and Development Methods and Technology Drug Targets Oncoprotein & tumor suppressor drug targets Gene Regulation Posttranscriptional and translational control Hematological Cancers Leukemias Oncogenes & Tumor Suppressors Oncogenes Preclinical Models Xenograft models Small Molecule Agents Stem Cell Biology Cancer stem cells Hematopoiesis |
| dc.title.none.fl_str_mv | Supplementary Table S7 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target |
| dc.type.none.fl_str_mv | Dataset info:eu-repo/semantics/publishedVersion dataset |
| description | <p>Table S7 shows (a) reproducible peaks and (b) GO analysis of ELAVL1-bound transcripts identified in the eCLIP-sequencing data set. The negatively enriched (c) and positively-enriched (d) gene sets identified by GSEA of ELAVL1-bound and differentially expressed transcripts from the RN2c RNA-sequencing data set are shown.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_949630691e2e2bcf85b9be4978f38bb7 |
| identifier_str_mv | 10.1158/2643-3230.30698685 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30698685 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY |
| spelling | Supplementary Table S7 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic TargetAna Vujovic (15207479)Laura de Rooij (15207482)Ava Keyvani Chahi (15207485)He Tian Chen (15207488)Brian A. Yee (15207491)Sampath K. Loganathan (15121740)Lina Liu (15207494)Derek C.H. Chan (15207497)Amanda Tajik (15207500)Emily Tsao (15207503)Steven Moreira (14937143)Pratik Joshi (15207506)Joshua Xu (15207509)Nicholas Wong (15207512)Zaldy Balde (15207515)Soheil Jahangiri (15207518)Sasan Zandi (15207521)Stefan Aigner (15207524)John E. Dick (14937554)Mark D. Minden (14961936)Daniel Schramek (15121764)Gene W. Yeo (15207527)Kristin J. Hope (15207530)CancerCancer BiologyMolecular and Cellular BiologyTherapeutic Research and DevelopmentMethods and TechnologyDrug TargetsOncoprotein & tumor suppressor drug targetsGene RegulationPosttranscriptional and translational controlHematological CancersLeukemiasOncogenes & Tumor SuppressorsOncogenesPreclinical ModelsXenograft modelsSmall Molecule AgentsStem Cell BiologyCancer stem cellsHematopoiesis<p>Table S7 shows (a) reproducible peaks and (b) GO analysis of ELAVL1-bound transcripts identified in the eCLIP-sequencing data set. The negatively enriched (c) and positively-enriched (d) gene sets identified by GSEA of ELAVL1-bound and differentially expressed transcripts from the RN2c RNA-sequencing data set are shown.</p>2025-11-24T22:02:24ZDatasetinfo:eu-repo/semantics/publishedVersiondataset10.1158/2643-3230.30698685https://figshare.com/articles/dataset/Supplementary_Table_S7_from_i_In_Vivo_i_Screening_Unveils_Pervasive_RNA-Binding_Protein_Dependencies_in_Leukemic_Stem_Cells_and_Identifies_ELAVL1_as_a_Therapeutic_Target/30698685CC BYinfo:eu-repo/semantics/openAccessoai:figshare.com:article/306986852025-11-24T22:02:24Z |
| spellingShingle | Supplementary Table S7 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target Ana Vujovic (15207479) Cancer Cancer Biology Molecular and Cellular Biology Therapeutic Research and Development Methods and Technology Drug Targets Oncoprotein & tumor suppressor drug targets Gene Regulation Posttranscriptional and translational control Hematological Cancers Leukemias Oncogenes & Tumor Suppressors Oncogenes Preclinical Models Xenograft models Small Molecule Agents Stem Cell Biology Cancer stem cells Hematopoiesis |
| status_str | publishedVersion |
| title | Supplementary Table S7 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target |
| title_full | Supplementary Table S7 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target |
| title_fullStr | Supplementary Table S7 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target |
| title_full_unstemmed | Supplementary Table S7 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target |
| title_short | Supplementary Table S7 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target |
| title_sort | Supplementary Table S7 from <i>In Vivo</i> Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target |
| topic | Cancer Cancer Biology Molecular and Cellular Biology Therapeutic Research and Development Methods and Technology Drug Targets Oncoprotein & tumor suppressor drug targets Gene Regulation Posttranscriptional and translational control Hematological Cancers Leukemias Oncogenes & Tumor Suppressors Oncogenes Preclinical Models Xenograft models Small Molecule Agents Stem Cell Biology Cancer stem cells Hematopoiesis |