FACS analysis of p24 + cells across acute and chronic cohorts.
<p>FACS dot plots showing the p24 KC57-FITC/28B7-APC co-staining on CD4 T cells. Red dots represent p24 + cells and frequencies of p24 + cells in CD4 T cells are depicted for each individual of the Acute UD, Acute UD + 5, Chronic UD and Chronic UD + x cohorts, accordingly to the stage of ART i...
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2025
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| _version_ | 1849927626396794880 |
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| author | Tine Struyve (22683295) |
| author2 | Marion Pardons (6407921) Jozefien De Clercq (17737815) Liesbet Termote (22683298) Laurens Lambrechts (10532207) Ytse Noppe (22683301) Mathias Lichterfeld (57148) Sofie Rutsaert (10667718) Linos Vandekerckhove (105574) |
| author2_role | author author author author author author author author |
| author_facet | Tine Struyve (22683295) Marion Pardons (6407921) Jozefien De Clercq (17737815) Liesbet Termote (22683298) Laurens Lambrechts (10532207) Ytse Noppe (22683301) Mathias Lichterfeld (57148) Sofie Rutsaert (10667718) Linos Vandekerckhove (105574) |
| author_role | author |
| dc.creator.none.fl_str_mv | Tine Struyve (22683295) Marion Pardons (6407921) Jozefien De Clercq (17737815) Liesbet Termote (22683298) Laurens Lambrechts (10532207) Ytse Noppe (22683301) Mathias Lichterfeld (57148) Sofie Rutsaert (10667718) Linos Vandekerckhove (105574) |
| dc.date.none.fl_str_mv | 2025-11-25T18:40:25Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.ppat.1013702.s004 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/FACS_analysis_of_p24_cells_across_acute_and_chronic_cohorts_/30714883 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biochemistry Medicine Neuroscience Biotechnology Evolutionary Biology Ecology Cancer Infectious Diseases Plant Biology Virology Computational Biology phorbol myristate acetate integration selection mechanisms xlink "> persistence small reservoir sizes treatment initiation timing clonal expansion contributes art ), irrespective individuals treated shortly reservoir persistence early reservoir persistence clonal expansion started treatment pma ), art initiation viral reservoir treated individuals inducible reservoir individuals treated 1 reservoir suggesting post proviruses integrated progressively enriched one year major barrier longitudinal analysis heterochromatin regions five years chronic cohorts cell compartment antiretroviral therapy already detected |
| dc.title.none.fl_str_mv | FACS analysis of p24 + cells across acute and chronic cohorts. |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p>FACS dot plots showing the p24 KC57-FITC/28B7-APC co-staining on CD4 T cells. Red dots represent p24 + cells and frequencies of p24 + cells in CD4 T cells are depicted for each individual of the Acute UD, Acute UD + 5, Chronic UD and Chronic UD + x cohorts, accordingly to the stage of ART initiation (Fiebig II-III, Fiebig IV-V and Chronic).</p> <p>(TIF)</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_97f01be7301f7ee4fc37a8f1583f9cc7 |
| identifier_str_mv | 10.1371/journal.ppat.1013702.s004 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30714883 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | FACS analysis of p24 + cells across acute and chronic cohorts.Tine Struyve (22683295)Marion Pardons (6407921)Jozefien De Clercq (17737815)Liesbet Termote (22683298)Laurens Lambrechts (10532207)Ytse Noppe (22683301)Mathias Lichterfeld (57148)Sofie Rutsaert (10667718)Linos Vandekerckhove (105574)BiochemistryMedicineNeuroscienceBiotechnologyEvolutionary BiologyEcologyCancerInfectious DiseasesPlant BiologyVirologyComputational Biologyphorbol myristate acetateintegration selection mechanismsxlink "> persistencesmall reservoir sizestreatment initiation timingclonal expansion contributesart ), irrespectiveindividuals treated shortlyreservoir persistence earlyreservoir persistenceclonal expansionstarted treatmentpma ),art initiationviral reservoirtreated individualsinducible reservoirindividuals treated1 reservoirsuggesting postproviruses integratedprogressively enrichedone yearmajor barrierlongitudinal analysisheterochromatin regionsfive yearschronic cohortscell compartmentantiretroviral therapyalready detected<p>FACS dot plots showing the p24 KC57-FITC/28B7-APC co-staining on CD4 T cells. Red dots represent p24 + cells and frequencies of p24 + cells in CD4 T cells are depicted for each individual of the Acute UD, Acute UD + 5, Chronic UD and Chronic UD + x cohorts, accordingly to the stage of ART initiation (Fiebig II-III, Fiebig IV-V and Chronic).</p> <p>(TIF)</p>2025-11-25T18:40:25ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.ppat.1013702.s004https://figshare.com/articles/figure/FACS_analysis_of_p24_cells_across_acute_and_chronic_cohorts_/30714883CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307148832025-11-25T18:40:25Z |
| spellingShingle | FACS analysis of p24 + cells across acute and chronic cohorts. Tine Struyve (22683295) Biochemistry Medicine Neuroscience Biotechnology Evolutionary Biology Ecology Cancer Infectious Diseases Plant Biology Virology Computational Biology phorbol myristate acetate integration selection mechanisms xlink "> persistence small reservoir sizes treatment initiation timing clonal expansion contributes art ), irrespective individuals treated shortly reservoir persistence early reservoir persistence clonal expansion started treatment pma ), art initiation viral reservoir treated individuals inducible reservoir individuals treated 1 reservoir suggesting post proviruses integrated progressively enriched one year major barrier longitudinal analysis heterochromatin regions five years chronic cohorts cell compartment antiretroviral therapy already detected |
| status_str | publishedVersion |
| title | FACS analysis of p24 + cells across acute and chronic cohorts. |
| title_full | FACS analysis of p24 + cells across acute and chronic cohorts. |
| title_fullStr | FACS analysis of p24 + cells across acute and chronic cohorts. |
| title_full_unstemmed | FACS analysis of p24 + cells across acute and chronic cohorts. |
| title_short | FACS analysis of p24 + cells across acute and chronic cohorts. |
| title_sort | FACS analysis of p24 + cells across acute and chronic cohorts. |
| topic | Biochemistry Medicine Neuroscience Biotechnology Evolutionary Biology Ecology Cancer Infectious Diseases Plant Biology Virology Computational Biology phorbol myristate acetate integration selection mechanisms xlink "> persistence small reservoir sizes treatment initiation timing clonal expansion contributes art ), irrespective individuals treated shortly reservoir persistence early reservoir persistence clonal expansion started treatment pma ), art initiation viral reservoir treated individuals inducible reservoir individuals treated 1 reservoir suggesting post proviruses integrated progressively enriched one year major barrier longitudinal analysis heterochromatin regions five years chronic cohorts cell compartment antiretroviral therapy already detected |