Modulations in activity dynamics in pyramidal (Pyr) neuron (black lines) and parvalbumin (PV) interneuron (red lines) populations by disrupting the excitatory/inhibitory (E/I) balance with an increased number of Pyr neurons.

A. Typical pattern of the time course of neuronal activity in Pyr and PV populations with an E/I ratio of 3.5:1.0. Black and red dashed arrows represent the speed of decay for the Pyr and PV populations, respectively. Under this condition, activation in...

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Autor principal:	Nobuhiko Wagatsuma (494052) (author)
Altres autors:	Sou Nobukawa (801776) (author), Tomoki Kurikawa (228085) (author)
Publicat:	2025
Matèries:	Neuroscience Physiology Biological Sciences not elsewhere classified vasoactive intestinal polypeptide multiple neural systems heterogenous temporal coordinations different subtype neurons computational microcircuit model preferentially impaired gamma modulating neuronal dynamics pv population precedes pv ], somatostatin network activity regulation pv population size pv interneuron activity atypical neural activities som population size population size som ], pv populations neuronal activity gamma oscillations frequency activity pyramidal population widely observed visual cortex vip ]). two disorders three subtypes specific subtypes results suggest numerically explored information flow flow directions enhances beta distinct types
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Modulations in activity dynamics in pyramidal (Pyr) neuron (black lines) and parvalbumin (PV) interneuron (red lines) populations by disrupting the excitatory/inhibitory (E/I) balance with an increased number of Pyr neurons.

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