Modulations in activity dynamics in pyramidal (Pyr) neuron (black lines) and parvalbumin (PV) interneuron (red lines) populations by disrupting the excitatory/inhibitory (E/I) balance with an increased number of Pyr neurons.

Modulations in activity dynamics in pyramidal (Pyr) neuron (black lines) and parvalbumin (PV) interneuron (red lines) populations by disrupting the excitatory/inhibitory (E/I) balance with an increased number of Pyr neurons.

<p><b><i>A.</i></b> Typical pattern of the time course of neuronal activity in Pyr and PV populations with an E/I ratio of 3.5:1.0. Black and red dashed arrows represent the speed of decay for the Pyr and PV populations, respectively. Under this condition, activation in...

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Detalhes bibliográficos
Autor principal: Nobuhiko Wagatsuma (494052) (author)
Outros Autores: Sou Nobukawa (801776) (author), Tomoki Kurikawa (228085) (author)
Publicado em: 2025
Assuntos:
Neuroscience
Physiology
Biological Sciences not elsewhere classified
vasoactive intestinal polypeptide
multiple neural systems
heterogenous temporal coordinations
different subtype neurons
computational microcircuit model
preferentially impaired gamma
modulating neuronal dynamics
pv population precedes
pv ], somatostatin
network activity regulation
pv population size
pv interneuron activity
atypical neural activities
som population size
population size
som ],
pv populations
neuronal activity
gamma oscillations
frequency activity
pyramidal population
widely observed
visual cortex
vip ]).
two disorders
three subtypes
specific subtypes
results suggest
numerically explored
information flow
flow directions
enhances beta
distinct types
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