Image 3_An open-label, proof-of-mechanism trial evaluating a neuroactive steroid GABA modulator in tinnitus.tiff
<p>Imbalances of excitatory and inhibitory signaling within the central auditory pathways are hypothesized to underlie tinnitus pathophysiology. Neuroactive steroids, such as allopregnanolone, are positive allosteric modulators of GABA<sub>A</sub> receptors that regulate neuronal s...
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2025
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