First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity

The incorporation of silicon bioisosteres into pharmacological structures has been used as a strategy to improve the therapeutic potential of drugs. However, no secosteroidal silicon-containing VDR ligands have been developed. Here we report the design, synthesis, and biological activity of six anal...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Julian Loureiro (20357035) (author)
مؤلفون آخرون: Samuel Seoane (1695694) (author), Ivo E. Sampaio-Dias (6293594) (author), Carole Peluso-Iltis (236527) (author), Thierry Guiberteau (5250623) (author), Beatriz Brito (3447149) (author), Carlos Gregorio (17320180) (author), Román Pérez-Fernández (1695700) (author), Natacha Rochel (225991) (author), Antonio Mouriño (1451062) (author), José E. Rodríguez-Borges (7148444) (author)
منشور في: 2024
الموضوعات:
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