Figure 4 from Imaging Glioblastoma Response to Radiotherapy Using <sup>2</sup>H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism
<p>Histologic assessment of tumor cell death 48 hours following chemoradiotherapy treatment. Representative sections of A11 (<b>A–F</b>), S2 (<b>I–N</b>), and U87 (<b>Q–V</b>) tumors stained with hematoxylin and eosin (H&E; <b>A</b>, <b>...
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2025
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| Tóm tắt: | <p>Histologic assessment of tumor cell death 48 hours following chemoradiotherapy treatment. Representative sections of A11 (<b>A–F</b>), S2 (<b>I–N</b>), and U87 (<b>Q–V</b>) tumors stained with hematoxylin and eosin (H&E; <b>A</b>, <b>D</b>, <b>I</b>, <b>L</b>, <b>Q</b>, and <b>T</b>). The top panels show the whole brain section containing the tumor, and the bottom panels show a Multiplication symbol 10 magnification of part of the tumor area. The sections were co-stained for CC3 (<b>B</b>, <b>E</b>, <b>J</b>, <b>M</b>, <b>R</b>, and <b>U</b>) and TUNEL (<b>C</b>, <b>F</b>, <b>K</b>, <b>N</b>, <b>S</b>, and <b>V</b>). The percentage of CC3 (<b>G</b>, <b>O</b>, and <b>W</b>)- and TUNEL (<b>H</b>, <b>P</b>, and <b>X</b>)-positive cells pretreatment and 48 hours after the completion of treatment is shown for A11 (<b>G</b> and <b>H</b>), S2 (<b>O</b> and <b>P</b>), and U87 (<b>W</b> and <b>X</b>) tumors (<i>n</i> = 4 per group, drug treated and untreated). Data are shown as mean ± SD. **, <i>P</i> < 0.01; ***, <i>P</i> < 0.001.</p> |
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