Figure 4 from Imaging Glioblastoma Response to Radiotherapy Using <sup>2</sup>H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism
<p>Histologic assessment of tumor cell death 48 hours following chemoradiotherapy treatment. Representative sections of A11 (<b>A–F</b>), S2 (<b>I–N</b>), and U87 (<b>Q–V</b>) tumors stained with hematoxylin and eosin (H&E; <b>A</b>, <b>...
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2025
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| _version_ | 1849927639759847424 |
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| author | Friederike Hesse (14958870) |
| author2 | Alan J. Wright (14931815) Vencel Somai (14958873) Flaviu Bulat (14958876) Felix Kreis (14931818) Kevin M. Brindle (9752021) |
| author2_role | author author author author author |
| author_facet | Friederike Hesse (14958870) Alan J. Wright (14931815) Vencel Somai (14958873) Flaviu Bulat (14958876) Felix Kreis (14931818) Kevin M. Brindle (9752021) |
| author_role | author |
| dc.creator.none.fl_str_mv | Friederike Hesse (14958870) Alan J. Wright (14931815) Vencel Somai (14958873) Flaviu Bulat (14958876) Felix Kreis (14931818) Kevin M. Brindle (9752021) |
| dc.date.none.fl_str_mv | 2025-11-24T22:42:21Z |
| dc.identifier.none.fl_str_mv | 10.1158/0008-5472.30699278 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/Figure_4_from_Imaging_Glioblastoma_Response_to_Radiotherapy_Using_sup_2_sup_H_Magnetic_Resonance_Spectroscopy_Measurements_of_Fumarate_Metabolism/30699278 |
| dc.rights.none.fl_str_mv | CC BY info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Cancer Methods and Technology Imaging Imaging probes Magnetic resonance imaging (MRI) Small animal imaging |
| dc.title.none.fl_str_mv | Figure 4 from Imaging Glioblastoma Response to Radiotherapy Using <sup>2</sup>H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p>Histologic assessment of tumor cell death 48 hours following chemoradiotherapy treatment. Representative sections of A11 (<b>A–F</b>), S2 (<b>I–N</b>), and U87 (<b>Q–V</b>) tumors stained with hematoxylin and eosin (H&E; <b>A</b>, <b>D</b>, <b>I</b>, <b>L</b>, <b>Q</b>, and <b>T</b>). The top panels show the whole brain section containing the tumor, and the bottom panels show a Multiplication symbol 10 magnification of part of the tumor area. The sections were co-stained for CC3 (<b>B</b>, <b>E</b>, <b>J</b>, <b>M</b>, <b>R</b>, and <b>U</b>) and TUNEL (<b>C</b>, <b>F</b>, <b>K</b>, <b>N</b>, <b>S</b>, and <b>V</b>). The percentage of CC3 (<b>G</b>, <b>O</b>, and <b>W</b>)- and TUNEL (<b>H</b>, <b>P</b>, and <b>X</b>)-positive cells pretreatment and 48 hours after the completion of treatment is shown for A11 (<b>G</b> and <b>H</b>), S2 (<b>O</b> and <b>P</b>), and U87 (<b>W</b> and <b>X</b>) tumors (<i>n</i> = 4 per group, drug treated and untreated). Data are shown as mean ± SD. **, <i>P</i> < 0.01; ***, <i>P</i> < 0.001.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_9d866dfe2980c8b8baa41e0a72a906ef |
| identifier_str_mv | 10.1158/0008-5472.30699278 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30699278 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY |
| spelling | Figure 4 from Imaging Glioblastoma Response to Radiotherapy Using <sup>2</sup>H Magnetic Resonance Spectroscopy Measurements of Fumarate MetabolismFriederike Hesse (14958870)Alan J. Wright (14931815)Vencel Somai (14958873)Flaviu Bulat (14958876)Felix Kreis (14931818)Kevin M. Brindle (9752021)CancerMethods and TechnologyImagingImaging probesMagnetic resonance imaging (MRI)Small animal imaging<p>Histologic assessment of tumor cell death 48 hours following chemoradiotherapy treatment. Representative sections of A11 (<b>A–F</b>), S2 (<b>I–N</b>), and U87 (<b>Q–V</b>) tumors stained with hematoxylin and eosin (H&E; <b>A</b>, <b>D</b>, <b>I</b>, <b>L</b>, <b>Q</b>, and <b>T</b>). The top panels show the whole brain section containing the tumor, and the bottom panels show a Multiplication symbol 10 magnification of part of the tumor area. The sections were co-stained for CC3 (<b>B</b>, <b>E</b>, <b>J</b>, <b>M</b>, <b>R</b>, and <b>U</b>) and TUNEL (<b>C</b>, <b>F</b>, <b>K</b>, <b>N</b>, <b>S</b>, and <b>V</b>). The percentage of CC3 (<b>G</b>, <b>O</b>, and <b>W</b>)- and TUNEL (<b>H</b>, <b>P</b>, and <b>X</b>)-positive cells pretreatment and 48 hours after the completion of treatment is shown for A11 (<b>G</b> and <b>H</b>), S2 (<b>O</b> and <b>P</b>), and U87 (<b>W</b> and <b>X</b>) tumors (<i>n</i> = 4 per group, drug treated and untreated). Data are shown as mean ± SD. **, <i>P</i> < 0.01; ***, <i>P</i> < 0.001.</p>2025-11-24T22:42:21ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1158/0008-5472.30699278https://figshare.com/articles/figure/Figure_4_from_Imaging_Glioblastoma_Response_to_Radiotherapy_Using_sup_2_sup_H_Magnetic_Resonance_Spectroscopy_Measurements_of_Fumarate_Metabolism/30699278CC BYinfo:eu-repo/semantics/openAccessoai:figshare.com:article/306992782025-11-24T22:42:21Z |
| spellingShingle | Figure 4 from Imaging Glioblastoma Response to Radiotherapy Using <sup>2</sup>H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism Friederike Hesse (14958870) Cancer Methods and Technology Imaging Imaging probes Magnetic resonance imaging (MRI) Small animal imaging |
| status_str | publishedVersion |
| title | Figure 4 from Imaging Glioblastoma Response to Radiotherapy Using <sup>2</sup>H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism |
| title_full | Figure 4 from Imaging Glioblastoma Response to Radiotherapy Using <sup>2</sup>H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism |
| title_fullStr | Figure 4 from Imaging Glioblastoma Response to Radiotherapy Using <sup>2</sup>H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism |
| title_full_unstemmed | Figure 4 from Imaging Glioblastoma Response to Radiotherapy Using <sup>2</sup>H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism |
| title_short | Figure 4 from Imaging Glioblastoma Response to Radiotherapy Using <sup>2</sup>H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism |
| title_sort | Figure 4 from Imaging Glioblastoma Response to Radiotherapy Using <sup>2</sup>H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism |
| topic | Cancer Methods and Technology Imaging Imaging probes Magnetic resonance imaging (MRI) Small animal imaging |