The modelling framework for synaptic plasticity replicates proximal LTP induced by 10 Hz rMS protocol and predicts increasing LTP with higher stimulation frequency.

<p><i>(a)</i> Schematic of stimulation with electric field vector. <i>(b)</i> Mean LTP in the proximal stratum radiatum decreases with lower stimulation frequency; the induced LTP for 10 Hz rMS is in agreement with experimental data from Lenz (2015). <i>(c) - (h)&...

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Main Author: Nicholas Hananeia (22683665) (author)
Other Authors: Christian Ebner (1276467) (author), Christos Galanis (15210328) (author), Hermann Cuntz (32618) (author), Alexander Opitz (295799) (author), Andreas Vlachos (47497) (author), Peter Jedlicka (179938) (author)
Published: 2025
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Summary:<p><i>(a)</i> Schematic of stimulation with electric field vector. <i>(b)</i> Mean LTP in the proximal stratum radiatum decreases with lower stimulation frequency; the induced LTP for 10 Hz rMS is in agreement with experimental data from Lenz (2015). <i>(c) - (h)</i> Induction of LTP from 900 pulse rMS protocol at various frequencies. Strong LTP is only seen in the proximal dendrites, with LTP in the stratum radiatum rapidly decreasing with lower frequency.</p>