Image 1_Altered tactile abnormalities in children with ASD during tactile processing and recognition revealed by dynamic EEG features.pdf
Introduction<p>Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by sensory processing abnormalities, particularly in tactile perception, highlighting the need for objective screening methods beyond current subjective behavioral assessments.</p>Methods<p>...
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2025
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| _version_ | 1852016573228777472 |
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| author | Wenjie Wang (413433) |
| author2 | Yuan Liu (88411) Ping Shi (385845) Jiayu Zhang (128702) Guoyao Wang (22257439) Yuanyuan Li (18671) Wei Liu (20030) Dong Ming (401661) |
| author2_role | author author author author author author author |
| author_facet | Wenjie Wang (413433) Yuan Liu (88411) Ping Shi (385845) Jiayu Zhang (128702) Guoyao Wang (22257439) Yuanyuan Li (18671) Wei Liu (20030) Dong Ming (401661) |
| author_role | author |
| dc.creator.none.fl_str_mv | Wenjie Wang (413433) Yuan Liu (88411) Ping Shi (385845) Jiayu Zhang (128702) Guoyao Wang (22257439) Yuanyuan Li (18671) Wei Liu (20030) Dong Ming (401661) |
| dc.date.none.fl_str_mv | 2025-09-16T13:26:43Z |
| dc.identifier.none.fl_str_mv | 10.3389/fpsyt.2025.1611438.s001 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/Image_1_Altered_tactile_abnormalities_in_children_with_ASD_during_tactile_processing_and_recognition_revealed_by_dynamic_EEG_features_pdf/30138223 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Psychiatry (incl. Psychotherapy) ASD tactile processing ERP electrotactile EEG |
| dc.title.none.fl_str_mv | Image 1_Altered tactile abnormalities in children with ASD during tactile processing and recognition revealed by dynamic EEG features.pdf |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | Introduction<p>Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by sensory processing abnormalities, particularly in tactile perception, highlighting the need for objective screening methods beyond current subjective behavioral assessments.</p>Methods<p>This study developed a portable electro-tactile stimulation system with EEG to evaluate tactile processing differences in children with ASD (n=36) versus typically developing controls (n=36). </p>Results<p>Revealing significantly reduced ERP amplitudes at key processing stages: P200 at FP2 (F(1,70)=10.82, p=0.0454), N200 at F3 (F(1,70)=58.33, p<0.0001), and P300 at C4 (F(1,70)=45.62, p<0.0001). Topographic analysis identified pronounced group differences (>10ìV) across frontal, central, and parietal regions (F8, FC5/6, CP1/2/5/6, Pz, Oz), with ASD children exhibiting prolonged but less efficient tactile discrimination and compensatory prefrontal activation (FP2 CV: p=0.043). The paradigm demonstrated strong reliability (CV ICC: ASD=0.779, TD=0.729) and achieved 85.2% classification accuracy (AUC=0.91) using ANN, with optimal performance from F8 P300 features (sensitivity=87.5%, specificity=83.7%). </p>Discussion<p>These findings provide an objective, efficient (15-minute) screening method that advances understanding of tactile processing abnormalities in ASD and supports the development of physiological biomarkers for early identification, overcoming limitations of questionnaire-based approaches.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_a02aebfbcfdf2fdb88c64240628bc176 |
| identifier_str_mv | 10.3389/fpsyt.2025.1611438.s001 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30138223 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Image 1_Altered tactile abnormalities in children with ASD during tactile processing and recognition revealed by dynamic EEG features.pdfWenjie Wang (413433)Yuan Liu (88411)Ping Shi (385845)Jiayu Zhang (128702)Guoyao Wang (22257439)Yuanyuan Li (18671)Wei Liu (20030)Dong Ming (401661)Psychiatry (incl. Psychotherapy)ASDtactile processingERPelectrotactileEEGIntroduction<p>Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by sensory processing abnormalities, particularly in tactile perception, highlighting the need for objective screening methods beyond current subjective behavioral assessments.</p>Methods<p>This study developed a portable electro-tactile stimulation system with EEG to evaluate tactile processing differences in children with ASD (n=36) versus typically developing controls (n=36). </p>Results<p>Revealing significantly reduced ERP amplitudes at key processing stages: P200 at FP2 (F(1,70)=10.82, p=0.0454), N200 at F3 (F(1,70)=58.33, p<0.0001), and P300 at C4 (F(1,70)=45.62, p<0.0001). Topographic analysis identified pronounced group differences (>10ìV) across frontal, central, and parietal regions (F8, FC5/6, CP1/2/5/6, Pz, Oz), with ASD children exhibiting prolonged but less efficient tactile discrimination and compensatory prefrontal activation (FP2 CV: p=0.043). The paradigm demonstrated strong reliability (CV ICC: ASD=0.779, TD=0.729) and achieved 85.2% classification accuracy (AUC=0.91) using ANN, with optimal performance from F8 P300 features (sensitivity=87.5%, specificity=83.7%). </p>Discussion<p>These findings provide an objective, efficient (15-minute) screening method that advances understanding of tactile processing abnormalities in ASD and supports the development of physiological biomarkers for early identification, overcoming limitations of questionnaire-based approaches.</p>2025-09-16T13:26:43ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.3389/fpsyt.2025.1611438.s001https://figshare.com/articles/figure/Image_1_Altered_tactile_abnormalities_in_children_with_ASD_during_tactile_processing_and_recognition_revealed_by_dynamic_EEG_features_pdf/30138223CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/301382232025-09-16T13:26:43Z |
| spellingShingle | Image 1_Altered tactile abnormalities in children with ASD during tactile processing and recognition revealed by dynamic EEG features.pdf Wenjie Wang (413433) Psychiatry (incl. Psychotherapy) ASD tactile processing ERP electrotactile EEG |
| status_str | publishedVersion |
| title | Image 1_Altered tactile abnormalities in children with ASD during tactile processing and recognition revealed by dynamic EEG features.pdf |
| title_full | Image 1_Altered tactile abnormalities in children with ASD during tactile processing and recognition revealed by dynamic EEG features.pdf |
| title_fullStr | Image 1_Altered tactile abnormalities in children with ASD during tactile processing and recognition revealed by dynamic EEG features.pdf |
| title_full_unstemmed | Image 1_Altered tactile abnormalities in children with ASD during tactile processing and recognition revealed by dynamic EEG features.pdf |
| title_short | Image 1_Altered tactile abnormalities in children with ASD during tactile processing and recognition revealed by dynamic EEG features.pdf |
| title_sort | Image 1_Altered tactile abnormalities in children with ASD during tactile processing and recognition revealed by dynamic EEG features.pdf |
| topic | Psychiatry (incl. Psychotherapy) ASD tactile processing ERP electrotactile EEG |