Regulating Biocondensates within Synthetic Cells via Segregative Phase Separation

Living cells orchestrate a myriad of biological reactions within a highly complex and crowded environment. A major factor responsible for such seamless assembly is the preferential interactions between the constituent macromolecules, that can drive demixing to produce coexisting phases and thus prov...

Full description

Saved in:

Bibliographic Details
Main Author:	Chang Chen (30907) (author)
Other Authors:	Caroline M. Love (21191790) (author), Christopher F. Carnahan (21191793) (author), Ketan A. Ganar (16984745) (author), Atul N. Parikh (169046) (author), Siddharth Deshpande (705014) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Cell Biology Genetics Immunology Biological Sciences not elsewhere classified still largely unknown phase separation phenomena occurring simultaneously within major factor responsible global shape transformation distinct design principle chip microfluidic systems biological reactions within produce coexisting phases including membrane interaction multiple phases way multiple targeting agents spatial localization sized vesicles seamless assembly rich dynamics process initiation preferential interactions molecular recruiters molecular distribution molecular communication mimicking confinements lipid membrane lipid boundary isolated microenvironment highly complex hierarchical domains externally trigger drive demixing diffusive motion cytoplasmic space crowded environment constituent macromolecules
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!

Regulating Biocondensates within Synthetic Cells via Segregative Phase Separation

Similar Items