Reduction in the risk of contrast-induced nephropathy using enhanced external counter-pulsation in patients with chronic kidney disease
<p>To evaluate the efficacy of EECP in the prevention of contrast-induced nephropathy (CIN) in patients with chronic kidney disease (CKD).</p> <p>A prospective trial was undertaken in the participants. A total of 280 patients with an estimated glomerular filtration rate (eGFR) of &...
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2024
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| _version_ | 1852026400051036160 |
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| author | Chun-Mei Zeng (19738693) |
| author2 | Hong-Yu Pan (681889) Yan-Mei Zhao (19738696) Zheng Ling (1367106) Ming Liu (105953) Ying Feng (151159) |
| author2_role | author author author author author |
| author_facet | Chun-Mei Zeng (19738693) Hong-Yu Pan (681889) Yan-Mei Zhao (19738696) Zheng Ling (1367106) Ming Liu (105953) Ying Feng (151159) |
| author_role | author |
| dc.creator.none.fl_str_mv | Chun-Mei Zeng (19738693) Hong-Yu Pan (681889) Yan-Mei Zhao (19738696) Zheng Ling (1367106) Ming Liu (105953) Ying Feng (151159) |
| dc.date.none.fl_str_mv | 2024-09-25T11:40:32Z |
| dc.identifier.none.fl_str_mv | 10.6084/m9.figshare.27101926.v1 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/online_resource/Reduction_in_the_risk_of_contrast-induced_nephropathy_using_enhanced_external_counter-pulsation_in_patients_with_chronic_kidney_disease/27101926 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Medicine Cell Biology Physiology Ecology Immunology Developmental Biology Marine Biology Cancer Infectious Diseases Computational Biology Enhanced external counter-pulsation chronic kidney disease contrast-induced nephropathy efficacy |
| dc.title.none.fl_str_mv | Reduction in the risk of contrast-induced nephropathy using enhanced external counter-pulsation in patients with chronic kidney disease |
| dc.type.none.fl_str_mv | Text Online resource info:eu-repo/semantics/publishedVersion text |
| description | <p>To evaluate the efficacy of EECP in the prevention of contrast-induced nephropathy (CIN) in patients with chronic kidney disease (CKD).</p> <p>A prospective trial was undertaken in the participants. A total of 280 patients with an estimated glomerular filtration rate (eGFR) of <60 ml/min/1.73 m<sup>2</sup> who underwent percutaneous coronary artery procedures were enrolled and divided into two groups: the control group (<i>n</i> = 100) and the EECP group (<i>n</i> = 180). All patients received extracellular fluid volume expansion therapy with 0.9% normal saline, and patients in the EECP groups were also treated with EECP. The renal function indexes of the two groups were determined 48–72 h after coronary artery procedures.</p> <p>In the EECP group, the BUN and serum creatinine (Scr) after coronary artery procedures were significantly lower than those before coronary artery procedures (BUN: 8.4 ± 3.5 <i>vs.</i> 6.6 ± 2.7 mmol/L, <i>p</i> < 0.001; Scr: 151.9 ± 44.7 <i>vs.</i> 144.5 ± 48.3 μmol/L, <i>p</i> < 0.001), while the eGFR was significantly increased (43.6 ± 11.4 <i>vs.</i> 47.1 ± 13.9 ml/min/1.73 m<sup>2</sup>, <i>p</i> < 0.001). The degree of Scr elevation was lower in the EECP group than in the control group (12.4 ± 15.0 <i>vs.</i> 20.9 ± 24.8 μmol/L, <i>p</i> = 0.026). Additionally, the EECP group had a lower incidence of post-procedures Scr elevation than the control group (36.5 <i>vs.</i> 48.0%, <i>p</i> = 0.042), a higher incidence of post-procedures eGFR elevation (62.2 <i>vs.</i> 48.0%, <i>p</i> = 0.021), and a lower risk of CIN (1.1 <i>vs.</i> 6.0%, <i>p</i> = 0.019).</p> <p>EECP therapy has a protective effect on renal function and can reduce the risk of CIN in patients with CKD.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_a28d7bb2fe73e97e28359166a7cd5b03 |
| identifier_str_mv | 10.6084/m9.figshare.27101926.v1 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/27101926 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
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| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Reduction in the risk of contrast-induced nephropathy using enhanced external counter-pulsation in patients with chronic kidney diseaseChun-Mei Zeng (19738693)Hong-Yu Pan (681889)Yan-Mei Zhao (19738696)Zheng Ling (1367106)Ming Liu (105953)Ying Feng (151159)MedicineCell BiologyPhysiologyEcologyImmunologyDevelopmental BiologyMarine BiologyCancerInfectious DiseasesComputational BiologyEnhanced external counter-pulsationchronic kidney diseasecontrast-induced nephropathyefficacy<p>To evaluate the efficacy of EECP in the prevention of contrast-induced nephropathy (CIN) in patients with chronic kidney disease (CKD).</p> <p>A prospective trial was undertaken in the participants. A total of 280 patients with an estimated glomerular filtration rate (eGFR) of <60 ml/min/1.73 m<sup>2</sup> who underwent percutaneous coronary artery procedures were enrolled and divided into two groups: the control group (<i>n</i> = 100) and the EECP group (<i>n</i> = 180). All patients received extracellular fluid volume expansion therapy with 0.9% normal saline, and patients in the EECP groups were also treated with EECP. The renal function indexes of the two groups were determined 48–72 h after coronary artery procedures.</p> <p>In the EECP group, the BUN and serum creatinine (Scr) after coronary artery procedures were significantly lower than those before coronary artery procedures (BUN: 8.4 ± 3.5 <i>vs.</i> 6.6 ± 2.7 mmol/L, <i>p</i> < 0.001; Scr: 151.9 ± 44.7 <i>vs.</i> 144.5 ± 48.3 μmol/L, <i>p</i> < 0.001), while the eGFR was significantly increased (43.6 ± 11.4 <i>vs.</i> 47.1 ± 13.9 ml/min/1.73 m<sup>2</sup>, <i>p</i> < 0.001). The degree of Scr elevation was lower in the EECP group than in the control group (12.4 ± 15.0 <i>vs.</i> 20.9 ± 24.8 μmol/L, <i>p</i> = 0.026). Additionally, the EECP group had a lower incidence of post-procedures Scr elevation than the control group (36.5 <i>vs.</i> 48.0%, <i>p</i> = 0.042), a higher incidence of post-procedures eGFR elevation (62.2 <i>vs.</i> 48.0%, <i>p</i> = 0.021), and a lower risk of CIN (1.1 <i>vs.</i> 6.0%, <i>p</i> = 0.019).</p> <p>EECP therapy has a protective effect on renal function and can reduce the risk of CIN in patients with CKD.</p>2024-09-25T11:40:32ZTextOnline resourceinfo:eu-repo/semantics/publishedVersiontext10.6084/m9.figshare.27101926.v1https://figshare.com/articles/online_resource/Reduction_in_the_risk_of_contrast-induced_nephropathy_using_enhanced_external_counter-pulsation_in_patients_with_chronic_kidney_disease/27101926CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/271019262024-09-25T11:40:32Z |
| spellingShingle | Reduction in the risk of contrast-induced nephropathy using enhanced external counter-pulsation in patients with chronic kidney disease Chun-Mei Zeng (19738693) Medicine Cell Biology Physiology Ecology Immunology Developmental Biology Marine Biology Cancer Infectious Diseases Computational Biology Enhanced external counter-pulsation chronic kidney disease contrast-induced nephropathy efficacy |
| status_str | publishedVersion |
| title | Reduction in the risk of contrast-induced nephropathy using enhanced external counter-pulsation in patients with chronic kidney disease |
| title_full | Reduction in the risk of contrast-induced nephropathy using enhanced external counter-pulsation in patients with chronic kidney disease |
| title_fullStr | Reduction in the risk of contrast-induced nephropathy using enhanced external counter-pulsation in patients with chronic kidney disease |
| title_full_unstemmed | Reduction in the risk of contrast-induced nephropathy using enhanced external counter-pulsation in patients with chronic kidney disease |
| title_short | Reduction in the risk of contrast-induced nephropathy using enhanced external counter-pulsation in patients with chronic kidney disease |
| title_sort | Reduction in the risk of contrast-induced nephropathy using enhanced external counter-pulsation in patients with chronic kidney disease |
| topic | Medicine Cell Biology Physiology Ecology Immunology Developmental Biology Marine Biology Cancer Infectious Diseases Computational Biology Enhanced external counter-pulsation chronic kidney disease contrast-induced nephropathy efficacy |