Expression of KLRF1, LTK, VCAN in whole blood (log2 RNA expression) or lung tissue microarray sections (H-Score) containing samples from patients with idiopathic pulmonary fibrosis (IPF), hypersensitivity pneumonitis (HP), and systemic sclerosis-associated interstitial lung disease (SSc-ILD).

Statistical significance of blood RNA expression was determined using differential expression analysis via ‘limma’ and corrected using false discovery rate (FDR), with statistical significance indicated by FDR<0.05 (***). To determine statistical significance of H-scores, a linear mixed-...

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Bibliographic Details
Main Author:	Daniel He (3477920) (author)
Other Authors:	Casey P. Shannon (8786369) (author), Jeremy A. Hirota (4407877) (author), Kjetil Ask (91350) (author), Christopher J. Ryerson (9742990) (author), Scott J. Tebbutt (8786399) (author)
Published:	2024
Subjects:	Cell Biology Genetics Pharmacology Cancer Biological Sciences not elsewhere classified identified one transcript gene nanostring assay causing irreversible damage identifying diagnostic biomarkers genomic blood biomarkers better clinical biomarkers ilds differs depending idiopathic pulmonary fibrosis expression significantly higher div >< p pulmonary fibrosis whole blood diagnostic potential clinical management vcan </ taken together systemic sclerosis specific transcripts peripheral transcriptome ltk </ klrf1 </ investigate whether hypersensitivity pneumonitis extracellular matrix excessive deposition differentially expressed >) associated
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