ML trees of vIL-4 and interleukin-4 homologs from a selection of representative bird and reptilian genomes.

<p>(A) From amino acid alignment, built with IQTREE using the ‘Q.bird+I+G4’ model as selected by ModelFinder, ultrafast bootstrapping (1000 iterations). (B) From coding nucleotide alignment, built with IQTREE using the ‘GTR+I+R’ model as selected by ModelFinder, ultrafast bootstrapping (1000 i...

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Dettagli Bibliografici
Autore principale:	Jeremy D. Volkening (13030758) (author)
Altri autori:	Stephen J. Spatz (4341484) (author), Maricarmen Garcia (21772671) (author), Teresa A. Ross (2066359) (author), Daniel A. Maekawa (21772674) (author), Kenneth S. Rosenthal (21772677) (author), Ana C. Zamora (21772680) (author), April Skipper (21772683) (author), Julia R. Blakey (21772686) (author), Rashan Paudel (21772689) (author)
Pubblicazione:	2025
Soggetti:	Medicine Microbiology Genetics Evolutionary Biology Immunology Infectious Diseases Virology Biological Sciences not elsewhere classified suggested direct capture stimulation assay showed natural cytokine signaling macrophage cell line length cdna sequencing confirmed using lc cell culture compared intron gene structure tertiary levels based sequenced iltv genomes infectious laryngotracheitis virus enhance virus replication conserved gene structure div >< p 4 knockout compared viral genome predicted 8 ), il iltv genome expressing recombinant chicken il expressed viral il viral il 4 gene viral mimics precisely conserved highly expressed comparable levels 5 ), vertebrate il functional il vivo </ vivo ,</ vitro </ vertebrate interleukin vertebrate homologs subsequently identified results represent protein expression phylogenetic analyses persisting within perpetuating strategies parental strain mature transcript infected cells immune response galliformes </ functional interleukin first report computational modeling cellular receptors 4 homologs
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ML trees of vIL-4 and interleukin-4 homologs from a selection of representative bird and reptilian genomes.

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