The rabbit femoral neck cerclage model leads to local apoptosis in the rabbit femoral head.

<p>Micro-CT and Western blot (WB) analyses were conducted to assess structural changes in the femoral head and alterations in bone metabolism markers following femoral neck ligation in juvenile rabbits. Rabbits were sacrificed at 14 and 28 days post-ligation, and femoral head tissues were harv...

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Bibliographic Details
Main Author:	Jiafei Yang (19736131) (author)
Other Authors:	Tianjiu Zhang (15925466) (author), Xingtao Zhu (20613855) (author), Zhexi He (20613858) (author), Xu Jiang (1602100) (author), Song Yu (3073554) (author), Huajian Gu (20144457) (author)
Published:	2025
Subjects:	Biochemistry Medicine Cell Biology Genetics Molecular Biology Physiology Immunology Developmental Biology Marine Biology Cancer Science Policy Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified luciferase reporter assays femoral neck ligation disrupted blood supply assessed using qpcr improving bone repair xlink "> legg directly targeting chac2 bmscs inhibited hypoxia 5p inhibits hypoxia targeting chac2 regulating hypoxia promotes repair western blotting transfected bmscs study investigates results indicate reduced necrosis promising target overexpressing bmscs joint deformity induced apoptosis hypoxic exposure hypoxic conditions findings suggest enhancing osteogenesis early osteoarthritis bmscs ). bmsc apoptosis 5p mimics
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The rabbit femoral neck cerclage model leads to local apoptosis in the rabbit femoral head.

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