The treatment of RSK inhibitors attenuates ORF45-increased ability of cell migration.
<p>GFP-ORF45-overexpressing HEK293 cells (A), iSLK.Bac16 cells or iSLK.STOP45 cells undergoing Dox + NaB-induced lytic reactivation (B) and HEK293 cells infected with Bac16 or STOP45 virions (MOI = 10) (C) were subjected to a wound healing scratch assay in presence of DMSO, 10 μM BI-D1870 or 1...
Αποθηκεύτηκε σε:
| Κύριος συγγραφέας: | |
|---|---|
| Άλλοι συγγραφείς: | , , , , |
| Έκδοση: |
2025
|
| Θέματα: | |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|
| _version_ | 1849927641670352896 |
|---|---|
| author | Xiaojuan Li (351842) |
| author2 | Li Quan (177024) Rihong Zhou (22676690) Xiangpeng Liu (17898881) Ronit Sarid (186795) Ersheng Kuang (129028) |
| author2_role | author author author author author |
| author_facet | Xiaojuan Li (351842) Li Quan (177024) Rihong Zhou (22676690) Xiangpeng Liu (17898881) Ronit Sarid (186795) Ersheng Kuang (129028) |
| author_role | author |
| dc.creator.none.fl_str_mv | Xiaojuan Li (351842) Li Quan (177024) Rihong Zhou (22676690) Xiangpeng Liu (17898881) Ronit Sarid (186795) Ersheng Kuang (129028) |
| dc.date.none.fl_str_mv | 2025-11-24T18:34:15Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.ppat.1013737.s002 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/The_treatment_of_RSK_inhibitors_attenuates_ORF45-increased_ability_of_cell_migration_/30697676 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Microbiology Cell Biology Molecular Biology Biotechnology Immunology Developmental Biology Cancer Infectious Diseases Virology s2152a knockin abolish primary effusion lymphoma multicentric castleman disease kaposi &# 8217 mediated viral infection infected adherent cells differentiated b cells sequential cell detachment mediated kshv transmission kshv lytic replication adherent cells lytic replication viral transmission kshv transmission cell detachment b lymphocytes lytic cycle cell transmission taken together results demonstrated radically support natural donors key role key regulator etiological agent dependent manner cell contact cell adhesion associated herpesvirus |
| dc.title.none.fl_str_mv | The treatment of RSK inhibitors attenuates ORF45-increased ability of cell migration. |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p>GFP-ORF45-overexpressing HEK293 cells (A), iSLK.Bac16 cells or iSLK.STOP45 cells undergoing Dox + NaB-induced lytic reactivation (B) and HEK293 cells infected with Bac16 or STOP45 virions (MOI = 10) (C) were subjected to a wound healing scratch assay in presence of DMSO, 10 μM BI-D1870 or 10 μM SL0101 treatment. The representative images and the relative wound healing abilities were shown. *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001, t test.</p> <p>(TIF)</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_a78a42b9d520de4bf3ecb5ee5ff4e68c |
| identifier_str_mv | 10.1371/journal.ppat.1013737.s002 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30697676 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | The treatment of RSK inhibitors attenuates ORF45-increased ability of cell migration.Xiaojuan Li (351842)Li Quan (177024)Rihong Zhou (22676690)Xiangpeng Liu (17898881)Ronit Sarid (186795)Ersheng Kuang (129028)MicrobiologyCell BiologyMolecular BiologyBiotechnologyImmunologyDevelopmental BiologyCancerInfectious DiseasesVirologys2152a knockin abolishprimary effusion lymphomamulticentric castleman diseasekaposi &# 8217mediated viral infectioninfected adherent cellsdifferentiated b cellssequential cell detachmentmediated kshv transmissionkshv lytic replicationadherent cellslytic replicationviral transmissionkshv transmissioncell detachmentb lymphocyteslytic cyclecell transmissiontaken togetherresults demonstratedradically supportnatural donorskey rolekey regulatoretiological agentdependent mannercell contactcell adhesionassociated herpesvirus<p>GFP-ORF45-overexpressing HEK293 cells (A), iSLK.Bac16 cells or iSLK.STOP45 cells undergoing Dox + NaB-induced lytic reactivation (B) and HEK293 cells infected with Bac16 or STOP45 virions (MOI = 10) (C) were subjected to a wound healing scratch assay in presence of DMSO, 10 μM BI-D1870 or 10 μM SL0101 treatment. The representative images and the relative wound healing abilities were shown. *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001, t test.</p> <p>(TIF)</p>2025-11-24T18:34:15ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.ppat.1013737.s002https://figshare.com/articles/figure/The_treatment_of_RSK_inhibitors_attenuates_ORF45-increased_ability_of_cell_migration_/30697676CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/306976762025-11-24T18:34:15Z |
| spellingShingle | The treatment of RSK inhibitors attenuates ORF45-increased ability of cell migration. Xiaojuan Li (351842) Microbiology Cell Biology Molecular Biology Biotechnology Immunology Developmental Biology Cancer Infectious Diseases Virology s2152a knockin abolish primary effusion lymphoma multicentric castleman disease kaposi &# 8217 mediated viral infection infected adherent cells differentiated b cells sequential cell detachment mediated kshv transmission kshv lytic replication adherent cells lytic replication viral transmission kshv transmission cell detachment b lymphocytes lytic cycle cell transmission taken together results demonstrated radically support natural donors key role key regulator etiological agent dependent manner cell contact cell adhesion associated herpesvirus |
| status_str | publishedVersion |
| title | The treatment of RSK inhibitors attenuates ORF45-increased ability of cell migration. |
| title_full | The treatment of RSK inhibitors attenuates ORF45-increased ability of cell migration. |
| title_fullStr | The treatment of RSK inhibitors attenuates ORF45-increased ability of cell migration. |
| title_full_unstemmed | The treatment of RSK inhibitors attenuates ORF45-increased ability of cell migration. |
| title_short | The treatment of RSK inhibitors attenuates ORF45-increased ability of cell migration. |
| title_sort | The treatment of RSK inhibitors attenuates ORF45-increased ability of cell migration. |
| topic | Microbiology Cell Biology Molecular Biology Biotechnology Immunology Developmental Biology Cancer Infectious Diseases Virology s2152a knockin abolish primary effusion lymphoma multicentric castleman disease kaposi &# 8217 mediated viral infection infected adherent cells differentiated b cells sequential cell detachment mediated kshv transmission kshv lytic replication adherent cells lytic replication viral transmission kshv transmission cell detachment b lymphocytes lytic cycle cell transmission taken together results demonstrated radically support natural donors key role key regulator etiological agent dependent manner cell contact cell adhesion associated herpesvirus |