Effects of PAI-1 deficiency on skeletal muscles with the administration of adenine diets.

Effects of PAI-1 deficiency on skeletal muscles with the administration of adenine diets.

<p>(A) Grip strength in PAI-1<sup>+/+</sup> and PAI-1<sup>-/-</sup> mice ten weeks after the initiation of adenine administration. (B, C) Muscle mass in the whole body (B) and the lower limbs (C) in PAI-1<sup>+/+</sup> and PAI-1<sup>-/-</sup> mic...

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Bibliographic Details
Main Author:	Yuya Mizukami (6558758) (author)
Other Authors:	Naoyuki Kawao (181472) (author), Takashi Ohira (153053) (author), Kiyotaka Okada (226871) (author), Hisatoshi Yamao (19832233) (author), Osamu Matsuo (181485) (author), Hiroshi Kaji (540508) (author)
Published:	2024
Subjects:	Biochemistry Medicine Cell Biology Genetics Physiology Science Policy Hematology tibialis anterior muscles sup >-/-</ sup sup >+/+</ sup quantitative computed tomography present study investigated femoral microstructural parameters chronic kidney disease div >< p sarcopenia remain unknown plasminogen activator inhibitor often involves ckd muscle weight measurement grip strength test mice </ p 1 deficiency also muscle wasting induced induced renal dysfunction induced female mice induced male mice renal dysfunction muscle wasting grip strength female mice induced mice muscle mass body weight 1 deficiency induced sarcopenia induced decreases deficient mice trabecular bone tissue weights ten weeks sarcopenia caused partly related lower limbs inflammatory conditions food intake ckd state bone metabolism bone loss bone disorders bone disorder 1 may
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