Unifying four-pathway model of long-term synaptic plasticity reproduces frequency dependence of synaptic changes in hippocampal CA1 pyramidal cells evoked by local electrical Schaffer collateral stimulation
<p><i>(a)</i> Local electrical stimulation (i.e. Schaffer collateral synaptic stimulation) regions (blue purple and magenta) shown on schematic. There is no somatic stimulation. <i>(b)</i> Schaffer collateral weight change for 900 pulses delivered at 1, 10, 30, and 100...
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2025
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| सारांश: | <p><i>(a)</i> Local electrical stimulation (i.e. Schaffer collateral synaptic stimulation) regions (blue purple and magenta) shown on schematic. There is no somatic stimulation. <i>(b)</i> Schaffer collateral weight change for 900 pulses delivered at 1, 10, 30, and 100 Hz with inhibition active. Model (red) and data (black). <i>(c)</i> Same as b but with inhibition blocked. Model (red) and bicuculline data (black).</p> |
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