Figure 4 from Bcl-xL Is a Key Mediator of Apoptosis Following KRAS<sup>G12C</sup> Inhibition in <i>KRAS<sup>G12C</sup></i>-mutant Colorectal Cancer

Figure 4 from Bcl-xL Is a Key Mediator of Apoptosis Following KRAS<sup>G12C</sup> Inhibition in <i>KRAS<sup>G12C</sup></i>-mutant Colorectal Cancer

<p>High-throughput drug screen reveals that pharmacologic inhibition of Bcl-xL synergizes with KRAS<sup>G12C</sup> inhibition in <i>KRAS</i><sup>G12C</sup> MT colorectal cancer. <b>A,</b> SW837 and SNU1411 cells were cotreated with 1 μmol/L AZ’15...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Hajrah Khawaja (15090810) (author)
مؤلفون آخرون:	Rebecca Briggs (15090813) (author), Cheryl H. Latimer (15090816) (author), Mustasin Rassel (15090819) (author), Daryl Griffin (15090822) (author), Lyndsey Hanson (15090825) (author), Alberto Bardelli (15046646) (author), Frederica Di Nicolantonio (15090828) (author), Simon S. McDade (14939679) (author), Christopher J. Scott (15090831) (author), Shauna Lambe (15090834) (author), Manisha Maurya (15090837) (author), Andreas U. Lindner (15033719) (author), Jochen H.M. Prehn (15033731) (author), Jose Sousa (15090840) (author), Chris Winnington (15090843) (author), Melissa J. LaBonte (15090846) (author), Sarah Ross (15090849) (author), Sandra Van Schaeybroeck (15090852) (author)
منشور في:	2025
الموضوعات:	Cancer Cancer Biology Therapeutic Research and Development Drug Resistance Novel mechanisms Gastrointestinal Cancers Colorectal cancer Oncogenes & Tumor Suppressors Kras
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!