The plasticity direction differs between Up/Downbound micromodules.

The plasticity direction differs between Up/Downbound micromodules.

<p><b>(A)</b> BCM mechanism: the x-axis represents the activity of the PC, and the y-axis represents the predicted plasticity change at a PF-PC synapse before scaling by PF activity. Positive values indicate potentiation; negative values indicate depression. Each gray curve shows t...

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Detalhes bibliográficos
Autor principal: Elías M. Fernández Santoro (22470299) (author)
Outros Autores: Lennart P.L. Landsmeer (22470302) (author), Said Hamdioui (21739013) (author), Christos Strydis (8270760) (author), Chris I. De Zeeuw (7304621) (author), Aleksandra Badura (252212) (author), Mario Negrello (4451539) (author)
Publicado em: 2025
Assuntos:
Cell Biology
Neuroscience
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
unique molecular profiles
frequency band pfs
homeostatic bidirectional plasticity
examine plasticity dynamics
cerebellar nuclei neurons
high intrinsic firing
downbound modules determine
synaptic dynamics necessary
downbound cerebellar micromodules
io neurons participating
synaptic plasticity
downbound micromodules
io neurons
baseline firing
downbound zones
synaptic weights
downbound pcs
weeks depending
stochastic input
stabilizing mechanisms
stabilized optimally
results indicate
relatively low
purkinje cell
overall strength
organized loops
inferior olive
highly adaptable
differential levels
different levels
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