The plasticity direction differs between Up/Downbound micromodules.

<p><b>(A)</b> BCM mechanism: the x-axis represents the activity of the PC, and the y-axis represents the predicted plasticity change at a PF-PC synapse before scaling by PF activity. Positive values indicate potentiation; negative values indicate depression. Each gray curve shows t...

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Autor principal:	Elías M. Fernández Santoro (22470299) (author)
Altres autors:	Lennart P.L. Landsmeer (22470302) (author), Said Hamdioui (21739013) (author), Christos Strydis (8270760) (author), Chris I. De Zeeuw (7304621) (author), Aleksandra Badura (252212) (author), Mario Negrello (4451539) (author)
Publicat:	2025
Matèries:	Cell Biology Neuroscience Biological Sciences not elsewhere classified Information Systems not elsewhere classified unique molecular profiles frequency band pfs homeostatic bidirectional plasticity examine plasticity dynamics cerebellar nuclei neurons high intrinsic firing downbound modules determine synaptic dynamics necessary downbound cerebellar micromodules io neurons participating synaptic plasticity downbound micromodules io neurons baseline firing downbound zones synaptic weights downbound pcs weeks depending stochastic input stabilizing mechanisms stabilized optimally results indicate relatively low purkinje cell overall strength organized loops inferior olive highly adaptable differential levels different levels
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The plasticity direction differs between Up/Downbound micromodules.

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