A list of final selected B cell peptides, including their position and immunological properties.

A list of final selected B cell peptides, including their position and immunological properties.

<p>A list of final selected B cell peptides, including their position and immunological properties.</p>

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Saurav Kumar Mishra (13228369) (author)
مؤلفون آخرون:	Kanishka Sithira Senathilake (20797077) (author), Neeraj Kumar (109718) (author), Chirag N. Patel (4722756) (author), Mohammad Borhan Uddin (20797080) (author), Taha Alqahtani (12855941) (author), Ali Alqahtani (7039244) (author), Hanan M. Alharbi (17357516) (author), John J. Georrge (4722759) (author)
منشور في:	2025
الموضوعات:	Medicine Microbiology Molecular Biology Biotechnology Immunology Infectious Diseases Virology Biological Sciences not elsewhere classified severe health issue prospective physiochemical characteristics mol binding energy immunological evaluation demonstrated igm +&# 8201 identified one b human immunodeficiency virus conjoined concurrently using 284 amino acids 1 envelope glycoprotein strong molecular interaction gpgpg ), including epitope subunit vaccine developed vaccine stimulates designed vaccine expression robust immune response immune response aids ), specific vaccine immune reaction widespread pandemic viroinformatics approach tlr3 shows tertiary structures specific linker research sought putative epitopes protective potency pet28a (+)) overall investigation multiple epitopes md simulation laboratory analysis ii epitopes hiv ); gc content four mhc exploratory algorithms examining hiv eight mhc docking analysis devise multi cell interaction c terminal assisted screening 100ns ).
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مواد مشابهة

The computed immunological and physicochemical features of the constructed vaccine.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

List of selected overlapped peptides from MHC-I and MHC-II with their restricted position, sequence, alleles, and immunological properties.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

List of refined models obtained by GalaxyRefine along with different attributes.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

Assessment of vaccine-generated immune response via C-ImmSim.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

An illustration of the cloned vaccine in the plasmid vector.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

Representation of stability and interaction energy of the complex between TLR3 and the vaccine.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

The simulation assessment of docked complex (TLR-3 and vaccine).
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

An illustration of molecular interaction activity within the docked complex (TLR3-Vaccine).
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

The structural flexibility analysis of the designed vaccine: (A) An estimated superimposed vaccine models, and (B) The summary of expected root mean square deviation within the designed vaccine model followed by higher and lower fluctuation.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

Illustration of the Disulfide bond formulation in the vaccine.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

Illustration of the identified conformational epitopes within the constructed vaccine in which the yellow sphere represents the epitopic region.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

The structural validation of the refined vaccine model.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

An illustration of the tertiary structure of constructed vaccine candidate (A) The constructed initial structure of vaccine candidate (B) Illustration of improved vaccine structure via refinements.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

A graphic illustration of the secondary structure considering strand, helix, and coil.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

A graphical illustration of epitope-based vaccine construction.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

Illustration of the anticipated chronology of procedures in this work.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

Illustration of 3D structure assessments of vaccine refined model.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

Representation of predicted B cell epitopes in the target protein via BepiPred 2.0 Server; yellow represents the epitopic, and green represents the non-epitopic region.
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

Data Sheet 1_An integrated mutation-based immunoinformatic approach incorporating variability in epitopes: a study based on HIV subtype C.docx
حسب: Saurav Kumar Mishra (13228369)
منشور في: (2025)

Predicted graphs of the immunological response following the administration of three doses of the proposed vaccine.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

Binding free energy values for the vaccine-TLR4 complex.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

List of discontinuous epitopes, with their scores and residue counts.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

Quality evaluation parameters of models refined by the GalaxyRefine server.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

The physicochemical parameters of the multi-epitope vaccine.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

<i>In silico</i> cloning of the vaccine cDNA sequence (blue) between the <i>XhoI</i> (158) and <i>XbaI</i> (806) restriction sites of the pET-28a (+) expression vector (black).
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

The MD simulation result for the vaccine-TLR4 complex.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

The molecular docking of the vaccine with TLR4.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

Visualization of discontinuous B-cell epitopes on the vaccine’s 3D structure.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

Validation of the vaccine candidate’s initial and refined 3D structural models.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

The refined three-dimensional structure of the multi-epitope vaccine.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

A graphical illustration of the secondary structure of the vaccine predicted by the PDBsum server.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

The solubility plot of the multi-epitope vaccine.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

Population coverage analysis of the selected T-cell epitopes based on their corresponding HLA alleles.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

The graphic illustration of the final configuration of the multi-epitope vaccine.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

Flowchart of the design of the multi-epitope vaccine in the current study.
حسب: Ramtin Naderian (22486368)
منشور في: (2025)

CA and CAT Cohorts: Summary of seven confirmed HLA-restricted epitopes compared to previous clinical trials.
حسب: Harini Ganeshan (83061)
منشور في: (2025)

Cohort CAT: FluoroSpot IFN-γ responses for non-protected participant v35 (HLA A*02:01 (A02)/A*02:06 (A02), B*39:05 (B27)/B*58:01 (B58) to AMA1 Ap8 peptide pool, 15mer component peptides, and synthesized predicted epitopes within active 15mers.
حسب: Harini Ganeshan (83061)
منشور في: (2025)

Cohort CAT: FluoroSpot IFN-γ and GzB responses for non-protected participant v33 (HLA A*23:01 (A24)/A*33:03 (A03), B*51:01 (B07)/B*58:01 (B58) to AMA1 Ap4, Ap8 and Ap10 peptide pools, 15mer peptides, and synthesized predicted epitopes.
حسب: Harini Ganeshan (83061)
منشور في: (2025)

Cohort CAT: FluoroSpot IFN-γ and GzB responses for protected participant v24 (HLA A*02:01 (A02)/A*30:01 (A01A03), B*35:01 (B07)/B*42:02 (B07) to AMA1 Ap1, Ap3 and Ap9 peptide pools, 15mer peptides, and synthesized predicted epitopes.
حسب: Harini Ganeshan (83061)
منشور في: (2025)

Cohort CAT: FluoroSpot IFN-γ and GzB responses for protected participant v12 (HLA A*02:02 (A02)/A*32:01 (A01), B*35:01 (B07)/B*44:03 (B44) to AMA1 Ap8 15mer peptide and synthesized predicted epitope.
حسب: Harini Ganeshan (83061)
منشور في: (2025)

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