Filamin A KO and S2152A KI reduce cell migration under ORF45 overexpression or during KSHV de novo infection or lytic reactivation.
<p>A-C. Filamin WT, S2152A KI or KO HEK293-mCherry cells were transfected with empty vector or ORF45 expressing plasmid for 24 h (A), or left uninfected or infected with iSLK.Bac16 or iSLK.STOP45 viral stocks (MOI = 10) for 24 h (B). The cells were subjected to a wound healing scratch assay, a...
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2025
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