Filamin A KO and S2152A KI reduce cell migration under ORF45 overexpression or during KSHV de novo infection or lytic reactivation.

<p>A-C. Filamin WT, S2152A KI or KO HEK293-mCherry cells were transfected with empty vector or ORF45 expressing plasmid for 24 h (A), or left uninfected or infected with iSLK.Bac16 or iSLK.STOP45 viral stocks (MOI = 10) for 24 h (B). The cells were subjected to a wound healing scratch assay, a...

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Bibliographische Detailangaben
1. Verfasser:	Xiaojuan Li (351842) (author)
Weitere Verfasser:	Li Quan (177024) (author), Rihong Zhou (22676690) (author), Xiangpeng Liu (17898881) (author), Ronit Sarid (186795) (author), Ersheng Kuang (129028) (author)
Veröffentlicht:	2025
Schlagworte:	Microbiology Cell Biology Molecular Biology Biotechnology Immunology Developmental Biology Cancer Infectious Diseases Virology s2152a knockin abolish primary effusion lymphoma multicentric castleman disease kaposi &# 8217 mediated viral infection infected adherent cells differentiated b cells sequential cell detachment mediated kshv transmission kshv lytic replication adherent cells lytic replication viral transmission kshv transmission cell detachment b lymphocytes lytic cycle cell transmission taken together results demonstrated radically support natural donors key role key regulator etiological agent dependent manner cell contact cell adhesion associated herpesvirus
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Filamin A KO and S2152A KI reduce cell migration under ORF45 overexpression or during KSHV de novo infection or lytic reactivation.

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