Porcine RVA (G5P[7], G9P[13]) levels in the small intestine (A) and large intestine (B); RVA shedding (rectal swabs) (C).
<p>Six-day-old germ-free pigs were orally inoculated with 1 × 106 FFU of each RVA. Swabs were collected at designated time points (day post-infection, dpi, 1-4). For the small and large intestine contents pigs were euthanized at the post-inoculation times indicated and contents were collected....
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2025
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| _version_ | 1849927626871799808 |
|---|---|
| author | Sergei A. Raev (15350287) |
| author2 | Maryssa K. Kick (17183901) Maria Chellis (22683628) Linda J. Saif (6626666) Talita P. Resende (3916268) Anastasia N. Vlasova (6626663) |
| author2_role | author author author author author |
| author_facet | Sergei A. Raev (15350287) Maryssa K. Kick (17183901) Maria Chellis (22683628) Linda J. Saif (6626666) Talita P. Resende (3916268) Anastasia N. Vlasova (6626663) |
| author_role | author |
| dc.creator.none.fl_str_mv | Sergei A. Raev (15350287) Maryssa K. Kick (17183901) Maria Chellis (22683628) Linda J. Saif (6626666) Talita P. Resende (3916268) Anastasia N. Vlasova (6626663) |
| dc.date.none.fl_str_mv | 2025-11-25T18:38:49Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.ppat.1013723.g001 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/Porcine_RVA_G5P_7_G9P_13_levels_in_the_small_intestine_A_and_large_intestine_B_RVA_shedding_rectal_swabs_C_/30714694 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biophysics Biochemistry Microbiology Ecology Infectious Diseases Space Science Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified increased sialic acid host characteristics regulate first experimental evidence findings may provide current global dominance rva rna detection multiple extraintestinal organs div >< p rva strains replicated related rva strains porcine osu g5p facilitating viral dissemination efficient extraintestinal spread rva receptor diversity rva extraintestinal spread examined extraintestinal tissues gut </ p extraintestinal tissues extraintestinal spread extraintestinal tissue extraintestinal sites also examined vivo </ vitro </ different tissues well understood respiratory lesions remarkably robust potential role pigs infected moderate titers microscopic lesions intestinal tissue inoculated germ highest titers highest frequency higher rate free pigs determine whether better understand |
| dc.title.none.fl_str_mv | Porcine RVA (G5P[7], G9P[13]) levels in the small intestine (A) and large intestine (B); RVA shedding (rectal swabs) (C). |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p>Six-day-old germ-free pigs were orally inoculated with 1 × 106 FFU of each RVA. Swabs were collected at designated time points (day post-infection, dpi, 1-4). For the small and large intestine contents pigs were euthanized at the post-inoculation times indicated and contents were collected. RVA quantification was performed using cell culture immunofluorescence (CCIF). Significant differences (*p < 0.05, ** p < 0.01, *** p < 0.001) are indicated as calculated by using two-way ANOVA with repeated measures and the Tukey-Kramer test for multiple comparisons.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_b0788fbdcefd945753197c53ae6018ce |
| identifier_str_mv | 10.1371/journal.ppat.1013723.g001 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30714694 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Porcine RVA (G5P[7], G9P[13]) levels in the small intestine (A) and large intestine (B); RVA shedding (rectal swabs) (C).Sergei A. Raev (15350287)Maryssa K. Kick (17183901)Maria Chellis (22683628)Linda J. Saif (6626666)Talita P. Resende (3916268)Anastasia N. Vlasova (6626663)BiophysicsBiochemistryMicrobiologyEcologyInfectious DiseasesSpace ScienceEnvironmental Sciences not elsewhere classifiedBiological Sciences not elsewhere classifiedincreased sialic acidhost characteristics regulatefirst experimental evidencefindings may providecurrent global dominancerva rna detectionmultiple extraintestinal organsdiv >< prva strains replicatedrelated rva strainsporcine osu g5pfacilitating viral disseminationefficient extraintestinal spreadrva receptor diversityrva extraintestinal spreadexamined extraintestinal tissuesgut </ pextraintestinal tissuesextraintestinal spreadextraintestinal tissueextraintestinal sitesalso examinedvivo </vitro </different tissueswell understoodrespiratory lesionsremarkably robustpotential rolepigs infectedmoderate titersmicroscopic lesionsintestinal tissueinoculated germhighest titershighest frequencyhigher ratefree pigsdetermine whetherbetter understand<p>Six-day-old germ-free pigs were orally inoculated with 1 × 106 FFU of each RVA. Swabs were collected at designated time points (day post-infection, dpi, 1-4). For the small and large intestine contents pigs were euthanized at the post-inoculation times indicated and contents were collected. RVA quantification was performed using cell culture immunofluorescence (CCIF). Significant differences (*p < 0.05, ** p < 0.01, *** p < 0.001) are indicated as calculated by using two-way ANOVA with repeated measures and the Tukey-Kramer test for multiple comparisons.</p>2025-11-25T18:38:49ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.ppat.1013723.g001https://figshare.com/articles/figure/Porcine_RVA_G5P_7_G9P_13_levels_in_the_small_intestine_A_and_large_intestine_B_RVA_shedding_rectal_swabs_C_/30714694CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307146942025-11-25T18:38:49Z |
| spellingShingle | Porcine RVA (G5P[7], G9P[13]) levels in the small intestine (A) and large intestine (B); RVA shedding (rectal swabs) (C). Sergei A. Raev (15350287) Biophysics Biochemistry Microbiology Ecology Infectious Diseases Space Science Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified increased sialic acid host characteristics regulate first experimental evidence findings may provide current global dominance rva rna detection multiple extraintestinal organs div >< p rva strains replicated related rva strains porcine osu g5p facilitating viral dissemination efficient extraintestinal spread rva receptor diversity rva extraintestinal spread examined extraintestinal tissues gut </ p extraintestinal tissues extraintestinal spread extraintestinal tissue extraintestinal sites also examined vivo </ vitro </ different tissues well understood respiratory lesions remarkably robust potential role pigs infected moderate titers microscopic lesions intestinal tissue inoculated germ highest titers highest frequency higher rate free pigs determine whether better understand |
| status_str | publishedVersion |
| title | Porcine RVA (G5P[7], G9P[13]) levels in the small intestine (A) and large intestine (B); RVA shedding (rectal swabs) (C). |
| title_full | Porcine RVA (G5P[7], G9P[13]) levels in the small intestine (A) and large intestine (B); RVA shedding (rectal swabs) (C). |
| title_fullStr | Porcine RVA (G5P[7], G9P[13]) levels in the small intestine (A) and large intestine (B); RVA shedding (rectal swabs) (C). |
| title_full_unstemmed | Porcine RVA (G5P[7], G9P[13]) levels in the small intestine (A) and large intestine (B); RVA shedding (rectal swabs) (C). |
| title_short | Porcine RVA (G5P[7], G9P[13]) levels in the small intestine (A) and large intestine (B); RVA shedding (rectal swabs) (C). |
| title_sort | Porcine RVA (G5P[7], G9P[13]) levels in the small intestine (A) and large intestine (B); RVA shedding (rectal swabs) (C). |
| topic | Biophysics Biochemistry Microbiology Ecology Infectious Diseases Space Science Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified increased sialic acid host characteristics regulate first experimental evidence findings may provide current global dominance rva rna detection multiple extraintestinal organs div >< p rva strains replicated related rva strains porcine osu g5p facilitating viral dissemination efficient extraintestinal spread rva receptor diversity rva extraintestinal spread examined extraintestinal tissues gut </ p extraintestinal tissues extraintestinal spread extraintestinal tissue extraintestinal sites also examined vivo </ vitro </ different tissues well understood respiratory lesions remarkably robust potential role pigs infected moderate titers microscopic lesions intestinal tissue inoculated germ highest titers highest frequency higher rate free pigs determine whether better understand |