Overview of scSCOPE Framework.

<p>(A) scSCOPE requires a gene expression matrix along with cluster annotations as input. (B) The input data undergoes Iterative Sparse Lasso Regression to identify genes capable of segregating two distinct groups. In each iteration of LASSO regression, data is split into training and testing...

Full description

Saved in:

Bibliographic Details
Main Author:	Sandesh Acharya (11261473) (author)
Other Authors:	Pathum Kossinna (17081585) (author), Qingrun Zhang (82414) (author), Jiami Guo (8755959) (author)
Published:	2025
Subjects:	Cell Biology Genetics Molecular Biology Cancer Plant Biology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Information Systems not elsewhere classified utilizes stabilized lasso specific marker genes least absolute shrinkage identified marker genes highest consistency across different sequencing technologies depth molecular insights becoming increasingly important reproducible marker genes consistency across datasets scscope &# 8217 cell transcriptomics datasets differential gene expression identify reproducible gene co cell type scrnaseq datasets xlink "> selection operator selected markers scscope outperforms rapid emergence present scscope pathway enrichments functional investigations functional annotations functional annotation feature selection expression networks experimental validation conventional methods bootstrapped co based platform analysis lack
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!

Overview of scSCOPE Framework.

Similar Items