Immune Infiltration and Association with Risk Score in HF Patients.

<p>(A) Immune infiltration analysis using CIBERSORT, IPS, and xCell, showing significant differences between HF patients and control samples, with more pronounced differences at higher risk score levels. (B) Correlation analysis between the risk score and 46 immune-related metrics, demonstrati...

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Bibliographic Details
Main Author:	Yiping Lang (21560364) (author)
Other Authors:	Tianyu Liang (8493861) (author), Fei Li (143236) (author)
Published:	2025
Subjects:	Medicine Cell Biology Genetics Molecular Biology Immunology Cancer Infectious Diseases Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified recent studies suggest provide new ideas pronounced alterations observed lasso cox regression highly advantageous method evaluated using cibersort elastic net regularization complex molecular alterations six key genes receiver operating characteristic individual genes across potential application value independent hf datasets characteristic genes related genes auc value validation datasets related datasets potential role potential biomarkers xlink "> study aimed single gene significantly higher screened may risk stratification risk score predictive modeling predicting hf integrated multi immune infiltration identified 340 hf patients hf based help improve heart failure gse5406 ). glmnet package gene signatures gene signature efficient values early diagnosis developed based combat algorithm clinical management cecal ligation cardiovascular dysfunction auc values 6 mice
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Immune Infiltration and Association with Risk Score in HF Patients.

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