Bacteremia levels in <i>B. miyamotoi</i>-injected mice.
<p>The bacteremia level in C57BL/6J (panels A and E), BALB/cJ (B and F), BALB/c-nude (C and G), and CB17SCID (D and H) mice are shown. A-D are the data of MYK2 A9-injected mice and E-H are the data of MYK4 C8-infected mice. The horizontal axis indicates the days post-inoculation, and the verti...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , |
| منشور في: |
2025
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| _version_ | 1852016129451491328 |
|---|---|
| author | Tomohi Takeuchi (22339791) |
| author2 | Yasuhiro Gotoh (8088848) Tetsuya Hayashi (45299) Hiroki Kawabata (269968) Ai Takano (613146) |
| author2_role | author author author author |
| author_facet | Tomohi Takeuchi (22339791) Yasuhiro Gotoh (8088848) Tetsuya Hayashi (45299) Hiroki Kawabata (269968) Ai Takano (613146) |
| author_role | author |
| dc.creator.none.fl_str_mv | Tomohi Takeuchi (22339791) Yasuhiro Gotoh (8088848) Tetsuya Hayashi (45299) Hiroki Kawabata (269968) Ai Takano (613146) |
| dc.date.none.fl_str_mv | 2025-09-30T17:46:34Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.ppat.1013514.g002 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/Bacteremia_levels_in_i_B_miyamotoi_i_-injected_mice_/30249714 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Microbiology Genetics Molecular Biology Biotechnology Evolutionary Biology Immunology Infectious Diseases Virology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified whole genome sequences multiple linear plasmids five linear plasmids five days post emerging infectious disease bacterial elimination depended downstream silent cassettes first cassette became like relapsing fever borne relapsing fever single gene conversion shows antigenic variation experimentally infected mice borrelia miyamotoi </ long segment conversion relapsing fever antigenic variation segment conversion gene cassettes miyamotoi </ borrelia </ gene cassette vmp </ plasmid segment long segment switch occurs switch occurred specific antibodies remains unknown mammalian hosts hard tick etiological agent clones reisolated carries clusters archival plasmid antibody production analyses revealed also show 16 kb |
| dc.title.none.fl_str_mv | Bacteremia levels in <i>B. miyamotoi</i>-injected mice. |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p>The bacteremia level in C57BL/6J (panels A and E), BALB/cJ (B and F), BALB/c-nude (C and G), and CB17SCID (D and H) mice are shown. A-D are the data of MYK2 A9-injected mice and E-H are the data of MYK4 C8-infected mice. The horizontal axis indicates the days post-inoculation, and the vertical axis indicates the copy number of <i>B. miyamotoi</i> 16S rDNA per ml of mouse whole blood. As <i>B. miyamotoi</i> contains only one <i>rrn</i> operon, the copy number of 16S rDNA roughly represents the number of <i>B. miyamotoi</i> bacterial cells.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_b4e1be6dff05ffaa7c58b6849f77e66a |
| identifier_str_mv | 10.1371/journal.ppat.1013514.g002 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30249714 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Bacteremia levels in <i>B. miyamotoi</i>-injected mice.Tomohi Takeuchi (22339791)Yasuhiro Gotoh (8088848)Tetsuya Hayashi (45299)Hiroki Kawabata (269968)Ai Takano (613146)MicrobiologyGeneticsMolecular BiologyBiotechnologyEvolutionary BiologyImmunologyInfectious DiseasesVirologyEnvironmental Sciences not elsewhere classifiedBiological Sciences not elsewhere classifiedwhole genome sequencesmultiple linear plasmidsfive linear plasmidsfive days postemerging infectious diseasebacterial elimination dependeddownstream silent cassettesfirst cassette becamelike relapsing feverborne relapsing feversingle gene conversionshows antigenic variationexperimentally infected miceborrelia miyamotoi </long segment conversionrelapsing feverantigenic variationsegment conversiongene cassettesmiyamotoi </borrelia </gene cassettevmp </plasmid segmentlong segmentswitch occursswitch occurredspecific antibodiesremains unknownmammalian hostshard ticketiological agentclones reisolatedcarries clustersarchival plasmidantibody productionanalyses revealedalso show16 kb<p>The bacteremia level in C57BL/6J (panels A and E), BALB/cJ (B and F), BALB/c-nude (C and G), and CB17SCID (D and H) mice are shown. A-D are the data of MYK2 A9-injected mice and E-H are the data of MYK4 C8-infected mice. The horizontal axis indicates the days post-inoculation, and the vertical axis indicates the copy number of <i>B. miyamotoi</i> 16S rDNA per ml of mouse whole blood. As <i>B. miyamotoi</i> contains only one <i>rrn</i> operon, the copy number of 16S rDNA roughly represents the number of <i>B. miyamotoi</i> bacterial cells.</p>2025-09-30T17:46:34ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.ppat.1013514.g002https://figshare.com/articles/figure/Bacteremia_levels_in_i_B_miyamotoi_i_-injected_mice_/30249714CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/302497142025-09-30T17:46:34Z |
| spellingShingle | Bacteremia levels in <i>B. miyamotoi</i>-injected mice. Tomohi Takeuchi (22339791) Microbiology Genetics Molecular Biology Biotechnology Evolutionary Biology Immunology Infectious Diseases Virology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified whole genome sequences multiple linear plasmids five linear plasmids five days post emerging infectious disease bacterial elimination depended downstream silent cassettes first cassette became like relapsing fever borne relapsing fever single gene conversion shows antigenic variation experimentally infected mice borrelia miyamotoi </ long segment conversion relapsing fever antigenic variation segment conversion gene cassettes miyamotoi </ borrelia </ gene cassette vmp </ plasmid segment long segment switch occurs switch occurred specific antibodies remains unknown mammalian hosts hard tick etiological agent clones reisolated carries clusters archival plasmid antibody production analyses revealed also show 16 kb |
| status_str | publishedVersion |
| title | Bacteremia levels in <i>B. miyamotoi</i>-injected mice. |
| title_full | Bacteremia levels in <i>B. miyamotoi</i>-injected mice. |
| title_fullStr | Bacteremia levels in <i>B. miyamotoi</i>-injected mice. |
| title_full_unstemmed | Bacteremia levels in <i>B. miyamotoi</i>-injected mice. |
| title_short | Bacteremia levels in <i>B. miyamotoi</i>-injected mice. |
| title_sort | Bacteremia levels in <i>B. miyamotoi</i>-injected mice. |
| topic | Microbiology Genetics Molecular Biology Biotechnology Evolutionary Biology Immunology Infectious Diseases Virology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified whole genome sequences multiple linear plasmids five linear plasmids five days post emerging infectious disease bacterial elimination depended downstream silent cassettes first cassette became like relapsing fever borne relapsing fever single gene conversion shows antigenic variation experimentally infected mice borrelia miyamotoi </ long segment conversion relapsing fever antigenic variation segment conversion gene cassettes miyamotoi </ borrelia </ gene cassette vmp </ plasmid segment long segment switch occurs switch occurred specific antibodies remains unknown mammalian hosts hard tick etiological agent clones reisolated carries clusters archival plasmid antibody production analyses revealed also show 16 kb |