<i>Dancr</i> regulates gene expression pathways involved in cell death.

<i>Dancr</i> regulates gene expression pathways involved in cell death.

<p>CRISPR-Cas9 mediated deletion of the zebrafish <i>dancr</i> promoter leads to a reduction in <i>dancr</i>, <i>snora26</i> and <i>snora27</i> expression. <b>(A)</b> Integrative Genomics Viewer visualisation of RNA-seq reads mapping...

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Bibliographic Details
Main Author:	Stephanie M. E. Jones (12883691) (author)
Other Authors:	Elizabeth A. Coe (8195508) (author), Michael Shapiro (80677) (author), Kelli M. Gallacher (22772681) (author), Karen Camargo Sosa (22772684) (author), Nikolas Nikolaou (21103869) (author), Igor Ulitsky (28697) (author), Robert N. Kelsh (42493) (author), Keith W. Vance (8195523) (author)
Published:	2025
Subjects:	Medicine Cell Biology Genetics Molecular Biology Immunology Developmental Biology Cancer Hematology Infectious Diseases Computational Biology Biological Sciences not elsewhere classified remains unclear whether positionally equivalent transcripts play crucial roles div >< p differentiation antagonizing non regulates genes involved exert similar roles lncrna transcription relative positionally equivalent lncrnas regulating gene expression diseases including cancer rna dancr </ associated lncrnas predicted syntenic long non early zebrafish development human melanoma oncogene long non dancr </ associated lncrna melanoma oncogene syntenic regions similar regions processes involved mitfa </ enriched lncrna zebrafish development organismal development embryonic development critical lncrnas melanoma patients identified melanoma human melanoma zebrafish genomes work suggests vertebrate genomes transcriptionally activated regulate human neighbouring protein functional investigation distant species developing embryo controls cancer cell death >, expressed
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