Flow chart of methodologies applied in the study.

<div><p>Background</p><p>Diabetic cardiomyopathy (DCM) represents a distinct myocardial pathology arising from chronic diabetic metabolic disturbances, characterized by progressive structural and functional abnormalities that frequently culminate in heart failure. Cuproptosis...

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Päätekijä:	Jun Li (6494) (author)
Muut tekijät:	Hua Zhang (12549) (author), Xinyue Duan (10184388) (author), Meina Zhang (654210) (author), Xin Li (51274) (author), Chunyan Hao (346539) (author)
Julkaistu:	2025
Aiheet:	Biochemistry Cell Biology Genetics Molecular Biology Developmental Biology Marine Biology Cancer Infectious Diseases Virology Computational Biology Biological Sciences not elsewhere classified respiratory electron transport pcr results showed mirna regulatory network including tca cycle auc )& gt bioinformatics analysis results isocitrate dehydrogenase 1 downloaded three datasets identified 14 defrgs verify hub genes potential candidate genes xlink "> overall protein interaction network differentially expressed cuproptosis dcm samples compared expression network analysis identified hub genes 7 key genes identify crgs involved cyp1a1 ), 3 hub genes xlink "> comprehensive analysis related genes 176 genes potential role pathways involved member 1 gse5606 datasets vitro model several pathways providing useful protein lipoylation progressive structural oxidative stress novel information novel form mitochondrial metabolism metabolism pathway highly linked high glucose hexokinase 2 heart failure gse5606 dataset geo database functional annotation functional abnormalities frequently culminate expression levels dcm diagnostic
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Flow chart of methodologies applied in the study.

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