Supplementary Figure S1 from Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma

Supplementary Figure S1 from Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma

<p>Detection of EBV-specific IgG in sera from incident NPC cases and healthy controls in the SCHS cohort. Heatmap depicting IgG heavy chain-specific (IgGH) normalized detection values from 20 incident NPC case-control pairs. The data is represented similarly to Fig 2 with Fisher’s exact test i...

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Autore principale: Sarita Paudel (15047430) (author)
Altri autori: Benjamin E. Warner (15047433) (author), Renwei Wang (15047436) (author), Jennifer Adams-Haduch (15047439) (author), Alex S. Reznik (15047442) (author), Jason Dou (15047445) (author), Yufei Huang (10791191) (author), Yu-Tang Gao (15047448) (author), Woon-Puay Koh (15047451) (author), Alan Bäckerholm (15047454) (author), Jian-Min Yuan (15047457) (author), Kathy H.Y. Shair (15047460) (author)
Pubblicazione: 2025
Soggetti:
Cancer
Cancer Biology
Cancer Detection and Diagnosis
Therapeutic Research and Development
Biomarkers
Cancer risk biomarkers
Serum biomarkers
Head, Neck & Oral Cancers
Translational Research
Viral Oncogenesis
Human tumor viruses
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Riassunto:<p>Detection of EBV-specific IgG in sera from incident NPC cases and healthy controls in the SCHS cohort. Heatmap depicting IgG heavy chain-specific (IgGH) normalized detection values from 20 incident NPC case-control pairs. The data is represented similarly to Fig 2 with Fisher’s exact test identifying proteins (bolded) that discriminate case from controls and denoted *p<0.05, **p<0.01, ***p<0.001.</p>

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