Flow Chart.
<div><p>Objective</p><p>To ascertain whether, in comparison to the participants’ expected abilities, the weather may cause abnormally poor cognitive or physical performance. Design Secondary analysis of a randomised controlled trial</p><p>Setting</p><p>...
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| _version_ | 1849927628972097536 |
|---|---|
| author | Jason Shourick (11436869) |
| author2 | Valérie Lauwers-Cances (14976678) Bruno Vellas (133953) Nicola Coley (4429804) Sandrine Andrieu (593534) |
| author2_role | author author author author |
| author_facet | Jason Shourick (11436869) Valérie Lauwers-Cances (14976678) Bruno Vellas (133953) Nicola Coley (4429804) Sandrine Andrieu (593534) |
| author_role | author |
| dc.creator.none.fl_str_mv | Jason Shourick (11436869) Valérie Lauwers-Cances (14976678) Bruno Vellas (133953) Nicola Coley (4429804) Sandrine Andrieu (593534) |
| dc.date.none.fl_str_mv | 2025-11-25T18:27:42Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.pone.0335866.g001 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/Flow_Chart_/30713697 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Medicine Neuroscience Biotechnology Evolutionary Biology Developmental Biology Science Policy Mental Health Infectious Diseases Virology subjective memory complaints slow gait speed participants &# 8217 individual &# 8217 design secondary analysis composite cognitive z abnormally low scores weather affects cognitive 13 memory centres xlink "> cognition free individuals aged significantly increased risk xlink "> weather conditions significantly increase 13 95 strongly considered results suggest physical performance physical outcomes physical function older adults mental state mapt trial instrumental activity included dementia grip strength false conclusions expected ability expected abilities clinical research clinical practice category fluency assessed using ascertain whether 70 years 15 95 |
| dc.title.none.fl_str_mv | Flow Chart. |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <div><p>Objective</p><p>To ascertain whether, in comparison to the participants’ expected abilities, the weather may cause abnormally poor cognitive or physical performance. Design Secondary analysis of a randomised controlled trial</p><p>Setting</p><p>Study conducted between May, 2008, and Feb, 2011 in 13 memory centres in France and Monaco</p><p>Participants</p><p>1313 participants from the MAPT trial, a 5-year multicentre prevention trial, which included dementia-free individuals aged over 70 years. Participants presented subjective memory complaints, slow gait speed and/or an instrumental activity of daily living limitation.</p><p>Main outcome measures</p><p>Cognition was assessed using a composite cognitive Z-score (composed of digit symbol substitution test, free and cued selective reminding test, Mini-mental state, category fluency) and subjective memory complaints. Physical function was assessed using gait speed, the short physical performance battery (SPPB) and its components, and grip strength. Abnormally low scores were defined as an observed score that was lower than the individual’s expected ability by at least the minimal clinically important difference.</p><p>Results</p><p>Higher outdoor temperature was associated with a significantly increased risk of abnormally low gait speed or SPPB (respectively OR 1.13 95% CI (1.04, 1.22) and OR 1.15 95% CI (1.03, 1.29) for 10 degrees Celsius), but did not significantly increase the risk of abnormally low cognitive function.</p><p>Conclusion</p><p>Our results suggest that weather conditions should be strongly considered when assessing the physical performance of older adults in the context of clinical practice and clinical research as examination in hot weather might lead to false conclusions on the participants’ abilities.</p></div> |
| eu_rights_str_mv | openAccess |
| id | Manara_b844b60c8a5b56f00e9927b194f4de9a |
| identifier_str_mv | 10.1371/journal.pone.0335866.g001 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30713697 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Flow Chart.Jason Shourick (11436869)Valérie Lauwers-Cances (14976678)Bruno Vellas (133953)Nicola Coley (4429804)Sandrine Andrieu (593534)MedicineNeuroscienceBiotechnologyEvolutionary BiologyDevelopmental BiologyScience PolicyMental HealthInfectious DiseasesVirologysubjective memory complaintsslow gait speedparticipants &# 8217individual &# 8217design secondary analysiscomposite cognitive zabnormally low scoresweather affects cognitive13 memory centresxlink "> cognitionfree individuals agedsignificantly increased riskxlink ">weather conditionssignificantly increase13 95strongly consideredresults suggestphysical performancephysical outcomesphysical functionolder adultsmental statemapt trialinstrumental activityincluded dementiagrip strengthfalse conclusionsexpected abilityexpected abilitiesclinical researchclinical practicecategory fluencyassessed usingascertain whether70 years15 95<div><p>Objective</p><p>To ascertain whether, in comparison to the participants’ expected abilities, the weather may cause abnormally poor cognitive or physical performance. Design Secondary analysis of a randomised controlled trial</p><p>Setting</p><p>Study conducted between May, 2008, and Feb, 2011 in 13 memory centres in France and Monaco</p><p>Participants</p><p>1313 participants from the MAPT trial, a 5-year multicentre prevention trial, which included dementia-free individuals aged over 70 years. Participants presented subjective memory complaints, slow gait speed and/or an instrumental activity of daily living limitation.</p><p>Main outcome measures</p><p>Cognition was assessed using a composite cognitive Z-score (composed of digit symbol substitution test, free and cued selective reminding test, Mini-mental state, category fluency) and subjective memory complaints. Physical function was assessed using gait speed, the short physical performance battery (SPPB) and its components, and grip strength. Abnormally low scores were defined as an observed score that was lower than the individual’s expected ability by at least the minimal clinically important difference.</p><p>Results</p><p>Higher outdoor temperature was associated with a significantly increased risk of abnormally low gait speed or SPPB (respectively OR 1.13 95% CI (1.04, 1.22) and OR 1.15 95% CI (1.03, 1.29) for 10 degrees Celsius), but did not significantly increase the risk of abnormally low cognitive function.</p><p>Conclusion</p><p>Our results suggest that weather conditions should be strongly considered when assessing the physical performance of older adults in the context of clinical practice and clinical research as examination in hot weather might lead to false conclusions on the participants’ abilities.</p></div>2025-11-25T18:27:42ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.pone.0335866.g001https://figshare.com/articles/figure/Flow_Chart_/30713697CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307136972025-11-25T18:27:42Z |
| spellingShingle | Flow Chart. Jason Shourick (11436869) Medicine Neuroscience Biotechnology Evolutionary Biology Developmental Biology Science Policy Mental Health Infectious Diseases Virology subjective memory complaints slow gait speed participants &# 8217 individual &# 8217 design secondary analysis composite cognitive z abnormally low scores weather affects cognitive 13 memory centres xlink "> cognition free individuals aged significantly increased risk xlink "> weather conditions significantly increase 13 95 strongly considered results suggest physical performance physical outcomes physical function older adults mental state mapt trial instrumental activity included dementia grip strength false conclusions expected ability expected abilities clinical research clinical practice category fluency assessed using ascertain whether 70 years 15 95 |
| status_str | publishedVersion |
| title | Flow Chart. |
| title_full | Flow Chart. |
| title_fullStr | Flow Chart. |
| title_full_unstemmed | Flow Chart. |
| title_short | Flow Chart. |
| title_sort | Flow Chart. |
| topic | Medicine Neuroscience Biotechnology Evolutionary Biology Developmental Biology Science Policy Mental Health Infectious Diseases Virology subjective memory complaints slow gait speed participants &# 8217 individual &# 8217 design secondary analysis composite cognitive z abnormally low scores weather affects cognitive 13 memory centres xlink "> cognition free individuals aged significantly increased risk xlink "> weather conditions significantly increase 13 95 strongly considered results suggest physical performance physical outcomes physical function older adults mental state mapt trial instrumental activity included dementia grip strength false conclusions expected ability expected abilities clinical research clinical practice category fluency assessed using ascertain whether 70 years 15 95 |