Broad-spectrum profiling of plasma miRNA at early (D1) and late stage of latency (D7).

Broad-spectrum profiling of plasma miRNA at early (D1) and late stage of latency (D7).

<p>(A) Multi-block sPLS-DA scatter plots, with miR block = plasma miRNA expression levels; macro block = cutaneous perfusion, TEWL, CRP, and CBC levels at D1 post-irradiation. (B) Multi-scale correlations between miRNA expression levels and clinical, functional, and biological analyses are ill...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Lucie Ancel (22022065) (author)
مؤلفون آخرون:	Jules Gueguen (22022068) (author), Guillaume Thoër (22022071) (author), Jules Marçais (22022074) (author), Aïda Chemloul (22022077) (author), Bernard Le Guen (10896352) (author), Marc Benderitter (168382) (author), Radia Tamarat (5965670) (author), Maâmar Souidi (6815306) (author), Mohamed Amine Benadjaoud (4172245) (author), Stéphane Flamant (14912708) (author)
منشور في:	2025
الموضوعات:	Biophysics Biochemistry Cell Biology Genetics Molecular Biology Neuroscience Biotechnology Immunology Developmental Biology Cancer Biological Sciences not elsewhere classified Physical Sciences not elsewhere classified symptom onset ranging refine mirna signatures prognostic mirna signatures clinical symptoms appear based biomarker signatures two latency stages identified candidate mirnas da ), signatures localized radiation injury mice </ p localized radiation injuries day 14 clinical early lri diagnosis lri severity prognosis mirnas ), localized injuries early diagnosis lri severity unrelated mice radiation response radiation exposure latency phase tissue injuries day 7 day 1 diagnosing lri xlink "> used throughout treatment outcomes tissue necrosis tissue damage severe outcomes previously associated presymptomatic microrna powerful tool performed broad mouse model irradiation ). hindlimb irradiation functional outcomes effective triage dose groups different severities adapted treatment 7 post
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مواد مشابهة

Targeted analysis of plasma miRNA at late stage of latency (D7).
حسب: Lucie Ancel (22022065)
منشور في: (2025)

Targeted analysis of plasma miRNAs at early stage of latency (D1).
حسب: Lucie Ancel (22022065)
منشور في: (2025)

Early signatures of localized radiation injury and correlations between early « latency » signatures and expected injury severity.
حسب: Lucie Ancel (22022065)
منشور في: (2025)

Common miRNAs of D1 and D7 signatures with their putative functions.
حسب: Lucie Ancel (22022065)
منشور في: (2025)

CBC at D7 post-irradiation.
حسب: Lucie Ancel (22022065)
منشور في: (2025)

CBC at D1 post-irradiation.
حسب: Lucie Ancel (22022065)
منشور في: (2025)

Clinical and biological monitoring.
حسب: Lucie Ancel (22022065)
منشور في: (2025)

Pathophysiology of the localized radiation injury at early timepoints.
حسب: Lucie Ancel (22022065)
منشور في: (2025)

Injury scores and laser Doppler skin perfusion ratios (IRR/NIR) at day-14 (from ref26).
حسب: Lucie Ancel (22022065)
منشور في: (2025)

Raw data of QC miRNAs and controls for each cohort.
حسب: Lucie Ancel (22022065)
منشور في: (2025)

Raw data for each cohort of the study.
حسب: Lucie Ancel (22022065)
منشور في: (2025)

<b>The Global Burden of </b><b><i>Klebsiella pneumoniae</i></b><b>-Associated Lower Respiratory Infection in 204 Countries and Territories, 1990–2021: Findings From the Global Burden of Disease Study 2021</b>
حسب: Kaizhi XU (20895128)
منشور في: (2025)

Global burden of antimicrobial resistance in lower respiratory infections in 2021: a systematic analysis
حسب: Xingyu Wan (20317727)
منشور في: (2024)

List of bionetworks enriched by a subset of <i>cnvd</i>-miRNA: Bionetworks significantly altered by the cumulative effects of RRiF and RD (RRiF *RD).
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

List of bionetworks enriched by a subset of <i>cnvd</i>-miRNA: Bionetworks significantly altered by the RRiF.
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

List of bionetworks enriched by a subset of <i>cnvd</i>-miRNA: Bionetworks significantly altered by the cumulative effects of sex, RD and TSI (sex*RD*TSI).
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

List of bionetworks enriched by a subset of <i>cnvd</i>-miRNA: Bionetworks significantly altered by the cumulative effects of RD and TSI (RD*TSI).
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

An miRNA panel to predict RRiF.
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

Functional association among the differentially expressed miRNA cluster linked to RRiF.
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

Functional association among the differentially expressed miRNA cluster linked to RD and TSI.
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

Putative miRNA markers of irradiation.
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

A flow diagram to explain the algorithm named 2BDP (Biomarker Discovery Process at Binomial Decision Point) that we used to find the best fitting model to predict RRiF.
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

A flow chart to depict the process to deliver miRNAs that were not only sequential homologues between humans and NHPs, but were also likely to respond similarly to irradiation across these two species.
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

Study design.
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

A. K-fold results: List of potential panels that can predict RRiF with AUC >0.85.
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

A. Correlation matrix of 11 networks that were significantly regulated by RD*TSI. Pearson correlation was calculated across radiation doses and TSI.
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

A. Number of differentially expressed (DE) miRNAs identified by 15 dependent and independent variables under 4-way ANOVA model.
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

S2 Fig -
حسب: Nabarun Chakraborty (535772)
منشور في: (2024)

Table 2_A panel of six immune-related mRNAs as biomarkers for tuberculosis diagnosis.xlsx
حسب: Yutong Wei (9512151)
منشور في: (2025)

Table 1_A panel of six immune-related mRNAs as biomarkers for tuberculosis diagnosis.docx
حسب: Yutong Wei (9512151)
منشور في: (2025)

Table 3_A panel of six immune-related mRNAs as biomarkers for tuberculosis diagnosis.xlsx
حسب: Yutong Wei (9512151)
منشور في: (2025)

Table 4_A panel of six immune-related mRNAs as biomarkers for tuberculosis diagnosis.xlsx
حسب: Yutong Wei (9512151)
منشور في: (2025)

Data Sheet 1_Serum miRNA-186-3P and miRNA-382-3P constitute a novel Diagnostic miRNA signature for palindromic rheumatism.docx
حسب: Fangfang Yuan (459230)
منشور في: (2025)

Demographics and clinical characteristics of the study cohort.
حسب: Antonio Marín-Romero (21453085)
منشور في: (2025)

Spearman’s correlation analysis:
حسب: Antonio Marín-Romero (21453085)
منشور في: (2025)

Biomarker profiles over the course of the liver event:
حسب: Antonio Marín-Romero (21453085)
منشور في: (2025)

Calibration Curve.
حسب: Antonio Marín-Romero (21453085)
منشور في: (2025)

Cartoon illustrating the general workflow of DCL.
حسب: Antonio Marín-Romero (21453085)
منشور في: (2025)

Additional file 4 of Instantaneous dose rate as a crucial factor in reducing mortality and normal tissue toxicities in murine total-body irradiation: a comparative study of dose rate combinations
حسب: Hongyu Zhu (4722834)
منشور في: (2025)

Additional file 3 of Instantaneous dose rate as a crucial factor in reducing mortality and normal tissue toxicities in murine total-body irradiation: a comparative study of dose rate combinations
حسب: Hongyu Zhu (4722834)
منشور في: (2025)

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