Figure 7 from Screening FDA-Approved Oncology Drugs with Three-Dimensional Spheroids Identifies Romidepsin as a Therapeutic Candidate for Osteosarcoma

Figure 7 from Screening FDA-Approved Oncology Drugs with Three-Dimensional Spheroids Identifies Romidepsin as a Therapeutic Candidate for Osteosarcoma

<p>Sarcospheres from a subset of patients are sensitive to romidepsin. Metabolic activity of sarcospheres from 18 human (<b>A</b>) and 10 canine (<b>B</b>) patients was measured after exposure for 48 hours to the indicated concentrations of romidepsin. Black curves repr...

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主要作者: Emily E. Seiden (22436851) (author)
其他作者: Spencer M. Richardson (22436854) (author), Leah A. Everitt (22436857) (author), Gabrielle J. Knafler (22436860) (author), Alyssa L. Walker (22436863) (author), Venetia A. Whiteside (22436866) (author), Divya Pillutla (22436869) (author), Shrey Ramnath (22436872) (author), Gavin P. Kinsella (22436875) (author), Piper A. Wilburn (22436878) (author), James D. Buschbach (22436881) (author), Deep A. Gandhi (22436884) (author), M. Reza Saadatzadeh (22436887) (author), L. Daniel Wurtz (22436890) (author), Patrick J. Getty (22436893) (author), Sheldon L. Padgett (22436896) (author), Rance M. Gamblin (22436899) (author), Michael O. Childress (22436902) (author), Christopher M. Fulkerson (15090300) (author), Maegan L. Capitano (22436905) (author), Karen E. Pollok (21365488) (author), Christopher D. Collier (21365482) (author), Edward M. Greenfield (22436908) (author)
出版: 2025
主題:
Cancer
Tumor Biology
Therapeutic Research and Development
Methods and Technology
Drug Discovery Technologies
Screening strategies (assays and chemical libraries)
In Vitro Models Of Cancer
Progression, Invasion & Metastasis
Tumor progression
Pediatric Cancers
Sarcomas
Osteosarcoma
Small Molecule Agents
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