Honolignols A–C, Three Racemic Forms of Honokiol-Derived Dimeric Neolignans from <i>Magnolia Officinalis</i> Var. <i>Biloba</i>

Honolignols A–C, Three Racemic Forms of Honokiol-Derived Dimeric Neolignans from <i>Magnolia Officinalis</i> Var. <i>Biloba</i>

Three pairs of racemic honokiol-derived dimeric neolignans, named honolignols A–C (<b>1</b>–<b>3</b>), featuring unique carbon skeletons, were isolated from the barks of <i>Magnolia officinalis</i> var. <i>biloba</i>. Honolignol A (<b>1</b>...

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Detalhes bibliográficos
Autor principal:	Wei-Ming Huang (7134713) (author)
Outros Autores:	Ping Ying (20876752) (author), Han-fei Gong (22651991) (author), Yue-You Yang (20403221) (author), Chuan-Lu Fu (22428605) (author), Ze Liu (130881) (author), Zi-wei Jia (22651994) (author), Zhen-Zhen Zhang (5042102) (author), Ling-Yi Kong (1344264) (author), Wen-Jun Xu (1596799) (author)
Publicado em:	2025
Assuntos:	Biophysics Biochemistry Microbiology Molecular Biology Environmental Sciences not elsewhere classified Chemical Sciences not elsewhere classified proposed biosynthetic pathway involving key radical exhibited antinonalcoholic steatohepatitis dioxapentacyclo [ 10 chiral hplc resolution bioactivity evaluation showed 2d nmr data magnolia officinalis </ compounds (+)/(−)-< b compound (−)-< b derived dimeric neolignans 9 ′– c 8 ′– c three racemic forms connecting two honokiol 4 ′′ linkages 3 </ b c (< b 2 </ b 1 </ b (< b biloba </ (+)-< b unprecedented 3 three pairs racemic honokiol derived units – c spectral comparisons relative configurations planar structures honokiol precursors comprehensive analysis absolute configurations 5 μm 4 ″ 20 μm
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