(related to Fig 2) Changes in behavioral readouts as a function of laser power in the easy discrimination task.
<p><b>A)</b> Average discrimination performance, <i>d’</i>, <b>B)</b> hit rate, and <b>C)</b> false alarm rate for all time window conditions. <b>D)</b> Normalized average discrimination performance, <i>d’</i>, in the ‘ent...
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2025
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| _version_ | 1849927627049009152 |
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| author | Lilia Kukovska (22683586) |
| author2 | Katharina A. Wilmes (22683589) Natsumi Y. Homma (22683592) Claudia Clopath (324706) Jasper Poort (22683595) |
| author2_role | author author author author |
| author_facet | Lilia Kukovska (22683586) Katharina A. Wilmes (22683589) Natsumi Y. Homma (22683592) Claudia Clopath (324706) Jasper Poort (22683595) |
| author_role | author |
| dc.creator.none.fl_str_mv | Lilia Kukovska (22683586) Katharina A. Wilmes (22683589) Natsumi Y. Homma (22683592) Claudia Clopath (324706) Jasper Poort (22683595) |
| dc.date.none.fl_str_mv | 2025-11-25T18:37:14Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.pbio.3003518.s005 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/_related_to_Fig_2_Changes_in_behavioral_readouts_as_a_function_of_laser_power_in_the_easy_discrimination_task_/30714538 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biochemistry Neuroscience Developmental Biology Science Policy Mental Health Biological Sciences not elsewhere classified xlink "> inhibition three major factors strong competitive interactions photon imaging showed balanced cortical activity primary visual cortex sustained v1 activity combined optogenetic activation v1 cells captured moderate pv activation moderate activation visual discriminations expressing cells nonlinear activation dependent activation activation strength task difficulty stimulus onset perceptual discrimination difficult discriminations delineates conditions circuit model behavioral effects |
| dc.title.none.fl_str_mv | (related to Fig 2) Changes in behavioral readouts as a function of laser power in the easy discrimination task. |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p><b>A)</b> Average discrimination performance, <i>d’</i>, <b>B)</b> hit rate, and <b>C)</b> false alarm rate for all time window conditions. <b>D)</b> Normalized average discrimination performance, <i>d’</i>, in the ‘entire’ window for sessions with lower hit rate (> 0.95). Shading, 95% CI of bootstrap distribution. Data is normalized by subtracting the value of the 0 power level during 0–2 s of stimulus onset. The same normalization method is applied across all normalized data plots regardless of the stimulation window duration. <b>E)</b> Normalized false alarm rate in the ‘entire’ window. Color lines, individual mice (<i>N</i> = 10, 41 sessions). <b>F)</b> Normalized discrimination performance, <i>d’</i>, in the ‘early’ window. Color lines, individual mice (<i>N</i> = 10, 37 sessions). <b>G)</b> Average discrimination performance, <i>d’</i>, in three mice, where high laser power (2 mW/mm<sup>2</sup>) was used to silence the ‘early’ window (6 sessions). As expected, two of three mice showed impaired performance. <b>H)</b> Average running speed for ‘go’ (continuous) and ‘no-go’ (interrupted) conditions for the mouse which retained high performance when the ‘early’ window was silenced at 2 mW/mm<sup>2</sup>. Running was delayed relative to stimulus presentation. In all plots, except D), error bars or shading indicate SEM.</p> <p>(TIFF)</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_ba9a6a5ec41895ce066f7af3d9764d0d |
| identifier_str_mv | 10.1371/journal.pbio.3003518.s005 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30714538 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | (related to Fig 2) Changes in behavioral readouts as a function of laser power in the easy discrimination task.Lilia Kukovska (22683586)Katharina A. Wilmes (22683589)Natsumi Y. Homma (22683592)Claudia Clopath (324706)Jasper Poort (22683595)BiochemistryNeuroscienceDevelopmental BiologyScience PolicyMental HealthBiological Sciences not elsewhere classifiedxlink "> inhibitionthree major factorsstrong competitive interactionsphoton imaging showedbalanced cortical activityprimary visual cortexsustained v1 activitycombined optogenetic activationv1 cells capturedmoderate pv activationmoderate activationvisual discriminationsexpressing cellsnonlinear activationdependent activationactivation strengthtask difficultystimulus onsetperceptual discriminationdifficult discriminationsdelineates conditionscircuit modelbehavioral effects<p><b>A)</b> Average discrimination performance, <i>d’</i>, <b>B)</b> hit rate, and <b>C)</b> false alarm rate for all time window conditions. <b>D)</b> Normalized average discrimination performance, <i>d’</i>, in the ‘entire’ window for sessions with lower hit rate (> 0.95). Shading, 95% CI of bootstrap distribution. Data is normalized by subtracting the value of the 0 power level during 0–2 s of stimulus onset. The same normalization method is applied across all normalized data plots regardless of the stimulation window duration. <b>E)</b> Normalized false alarm rate in the ‘entire’ window. Color lines, individual mice (<i>N</i> = 10, 41 sessions). <b>F)</b> Normalized discrimination performance, <i>d’</i>, in the ‘early’ window. Color lines, individual mice (<i>N</i> = 10, 37 sessions). <b>G)</b> Average discrimination performance, <i>d’</i>, in three mice, where high laser power (2 mW/mm<sup>2</sup>) was used to silence the ‘early’ window (6 sessions). As expected, two of three mice showed impaired performance. <b>H)</b> Average running speed for ‘go’ (continuous) and ‘no-go’ (interrupted) conditions for the mouse which retained high performance when the ‘early’ window was silenced at 2 mW/mm<sup>2</sup>. Running was delayed relative to stimulus presentation. In all plots, except D), error bars or shading indicate SEM.</p> <p>(TIFF)</p>2025-11-25T18:37:14ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.pbio.3003518.s005https://figshare.com/articles/figure/_related_to_Fig_2_Changes_in_behavioral_readouts_as_a_function_of_laser_power_in_the_easy_discrimination_task_/30714538CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307145382025-11-25T18:37:14Z |
| spellingShingle | (related to Fig 2) Changes in behavioral readouts as a function of laser power in the easy discrimination task. Lilia Kukovska (22683586) Biochemistry Neuroscience Developmental Biology Science Policy Mental Health Biological Sciences not elsewhere classified xlink "> inhibition three major factors strong competitive interactions photon imaging showed balanced cortical activity primary visual cortex sustained v1 activity combined optogenetic activation v1 cells captured moderate pv activation moderate activation visual discriminations expressing cells nonlinear activation dependent activation activation strength task difficulty stimulus onset perceptual discrimination difficult discriminations delineates conditions circuit model behavioral effects |
| status_str | publishedVersion |
| title | (related to Fig 2) Changes in behavioral readouts as a function of laser power in the easy discrimination task. |
| title_full | (related to Fig 2) Changes in behavioral readouts as a function of laser power in the easy discrimination task. |
| title_fullStr | (related to Fig 2) Changes in behavioral readouts as a function of laser power in the easy discrimination task. |
| title_full_unstemmed | (related to Fig 2) Changes in behavioral readouts as a function of laser power in the easy discrimination task. |
| title_short | (related to Fig 2) Changes in behavioral readouts as a function of laser power in the easy discrimination task. |
| title_sort | (related to Fig 2) Changes in behavioral readouts as a function of laser power in the easy discrimination task. |
| topic | Biochemistry Neuroscience Developmental Biology Science Policy Mental Health Biological Sciences not elsewhere classified xlink "> inhibition three major factors strong competitive interactions photon imaging showed balanced cortical activity primary visual cortex sustained v1 activity combined optogenetic activation v1 cells captured moderate pv activation moderate activation visual discriminations expressing cells nonlinear activation dependent activation activation strength task difficulty stimulus onset perceptual discrimination difficult discriminations delineates conditions circuit model behavioral effects |