Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.

<p>Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.</p>

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας: Ji-Xin Zhao (22056386) (author)
Άλλοι συγγραφείς: Wen-Bin Zheng (3328680) (author), Shi-Chen Xie (10678094) (author), He Ma (583317) (author), Xiao-Tong Chen (4217488) (author), Ying-Qian Gao (22683622) (author), Lu-Yao Tang (22683625) (author), Meng-Ting Yang (10714266) (author), Fu-Long Nan (22056395) (author), Jing Jiang (130103) (author), Hany M. Elsheikha (6910232) (author), Xiao-Xuan Zhang (610969) (author)
Έκδοση: 2025
Θέματα:
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_version_ 1849927625757163520
author Ji-Xin Zhao (22056386)
author2 Wen-Bin Zheng (3328680)
Shi-Chen Xie (10678094)
He Ma (583317)
Xiao-Tong Chen (4217488)
Ying-Qian Gao (22683622)
Lu-Yao Tang (22683625)
Meng-Ting Yang (10714266)
Fu-Long Nan (22056395)
Jing Jiang (130103)
Hany M. Elsheikha (6910232)
Xiao-Xuan Zhang (610969)
author2_role author
author
author
author
author
author
author
author
author
author
author
author_facet Ji-Xin Zhao (22056386)
Wen-Bin Zheng (3328680)
Shi-Chen Xie (10678094)
He Ma (583317)
Xiao-Tong Chen (4217488)
Ying-Qian Gao (22683622)
Lu-Yao Tang (22683625)
Meng-Ting Yang (10714266)
Fu-Long Nan (22056395)
Jing Jiang (130103)
Hany M. Elsheikha (6910232)
Xiao-Xuan Zhang (610969)
author_role author
dc.creator.none.fl_str_mv Ji-Xin Zhao (22056386)
Wen-Bin Zheng (3328680)
Shi-Chen Xie (10678094)
He Ma (583317)
Xiao-Tong Chen (4217488)
Ying-Qian Gao (22683622)
Lu-Yao Tang (22683625)
Meng-Ting Yang (10714266)
Fu-Long Nan (22056395)
Jing Jiang (130103)
Hany M. Elsheikha (6910232)
Xiao-Xuan Zhang (610969)
dc.date.none.fl_str_mv 2025-11-25T19:00:47Z
dc.identifier.none.fl_str_mv 10.1371/journal.pntd.0013768.s006
dc.relation.none.fl_str_mv https://figshare.com/articles/dataset/Pathway_enrichment_analysis_of_differential_metabolites_highlighting_significantly_impacted_metabolic_pathways_and_associated_enrichment_statistics_based_on_KEGG_or_other_pathway_databases_/30715233
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biochemistry
Microbiology
Cell Biology
Genetics
Physiology
Ecology
Immunology
Computational Biology
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
showed negative associations
quality reads produced
oxidative stress response
conducted metagenomic sequencing
compositional changes coincided
bile acid transformation
aromatic compound processing
7 million genes
rothia nasimurium </
lactobacillus intestinalis </
de novo </
untargeted serum metabolomics
specific metabolic disruptions
amino acid metabolism
toxoplasma gondii </
limosilactobacillus reuteri </
lactobacillus johnsonii </
akkermansia muciniphila </
host systemic metabolism
disrupts intestinal microbiota
reuteri </
muciniphila </
johnsonii </
gondii </
host metabolism
untargeted lc
metabolic targets
energy metabolism
infection disrupts
significant shifts
reduced abundance
rat model
positively correlated
pathways related
novel microbial
microbial diversity
metabolites implicated
marked reduction
marked depletion
key role
immune modulation
gut microbiota
findings demonstrate
enhanced glycan
disease mechanisms
comprehensive non
community structure
chronic stages
active enzymes
18 sprague
dc.title.none.fl_str_mv Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.
dc.type.none.fl_str_mv Dataset
info:eu-repo/semantics/publishedVersion
dataset
description <p>Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.</p>
eu_rights_str_mv openAccess
id Manara_baf72169951e84f677726006c88bc65f
identifier_str_mv 10.1371/journal.pntd.0013768.s006
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/30715233
publishDate 2025
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY 4.0
spelling Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.Ji-Xin Zhao (22056386)Wen-Bin Zheng (3328680)Shi-Chen Xie (10678094)He Ma (583317)Xiao-Tong Chen (4217488)Ying-Qian Gao (22683622)Lu-Yao Tang (22683625)Meng-Ting Yang (10714266)Fu-Long Nan (22056395)Jing Jiang (130103)Hany M. Elsheikha (6910232)Xiao-Xuan Zhang (610969)BiochemistryMicrobiologyCell BiologyGeneticsPhysiologyEcologyImmunologyComputational BiologyBiological Sciences not elsewhere classifiedChemical Sciences not elsewhere classifiedshowed negative associationsquality reads producedoxidative stress responseconducted metagenomic sequencingcompositional changes coincidedbile acid transformationaromatic compound processing7 million genesrothia nasimurium </lactobacillus intestinalis </de novo </untargeted serum metabolomicsspecific metabolic disruptionsamino acid metabolismtoxoplasma gondii </limosilactobacillus reuteri </lactobacillus johnsonii </akkermansia muciniphila </host systemic metabolismdisrupts intestinal microbiotareuteri </muciniphila </johnsonii </gondii </host metabolismuntargeted lcmetabolic targetsenergy metabolisminfection disruptssignificant shiftsreduced abundancerat modelpositively correlatedpathways relatednovel microbialmicrobial diversitymetabolites implicatedmarked reductionmarked depletionkey roleimmune modulationgut microbiotafindings demonstrateenhanced glycandisease mechanismscomprehensive noncommunity structurechronic stagesactive enzymes18 sprague<p>Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.</p>2025-11-25T19:00:47ZDatasetinfo:eu-repo/semantics/publishedVersiondataset10.1371/journal.pntd.0013768.s006https://figshare.com/articles/dataset/Pathway_enrichment_analysis_of_differential_metabolites_highlighting_significantly_impacted_metabolic_pathways_and_associated_enrichment_statistics_based_on_KEGG_or_other_pathway_databases_/30715233CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307152332025-11-25T19:00:47Z
spellingShingle Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.
Ji-Xin Zhao (22056386)
Biochemistry
Microbiology
Cell Biology
Genetics
Physiology
Ecology
Immunology
Computational Biology
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
showed negative associations
quality reads produced
oxidative stress response
conducted metagenomic sequencing
compositional changes coincided
bile acid transformation
aromatic compound processing
7 million genes
rothia nasimurium </
lactobacillus intestinalis </
de novo </
untargeted serum metabolomics
specific metabolic disruptions
amino acid metabolism
toxoplasma gondii </
limosilactobacillus reuteri </
lactobacillus johnsonii </
akkermansia muciniphila </
host systemic metabolism
disrupts intestinal microbiota
reuteri </
muciniphila </
johnsonii </
gondii </
host metabolism
untargeted lc
metabolic targets
energy metabolism
infection disrupts
significant shifts
reduced abundance
rat model
positively correlated
pathways related
novel microbial
microbial diversity
metabolites implicated
marked reduction
marked depletion
key role
immune modulation
gut microbiota
findings demonstrate
enhanced glycan
disease mechanisms
comprehensive non
community structure
chronic stages
active enzymes
18 sprague
status_str publishedVersion
title Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.
title_full Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.
title_fullStr Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.
title_full_unstemmed Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.
title_short Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.
title_sort Pathway enrichment analysis of differential metabolites, highlighting significantly impacted metabolic pathways and associated enrichment statistics based on KEGG or other pathway databases.
topic Biochemistry
Microbiology
Cell Biology
Genetics
Physiology
Ecology
Immunology
Computational Biology
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
showed negative associations
quality reads produced
oxidative stress response
conducted metagenomic sequencing
compositional changes coincided
bile acid transformation
aromatic compound processing
7 million genes
rothia nasimurium </
lactobacillus intestinalis </
de novo </
untargeted serum metabolomics
specific metabolic disruptions
amino acid metabolism
toxoplasma gondii </
limosilactobacillus reuteri </
lactobacillus johnsonii </
akkermansia muciniphila </
host systemic metabolism
disrupts intestinal microbiota
reuteri </
muciniphila </
johnsonii </
gondii </
host metabolism
untargeted lc
metabolic targets
energy metabolism
infection disrupts
significant shifts
reduced abundance
rat model
positively correlated
pathways related
novel microbial
microbial diversity
metabolites implicated
marked reduction
marked depletion
key role
immune modulation
gut microbiota
findings demonstrate
enhanced glycan
disease mechanisms
comprehensive non
community structure
chronic stages
active enzymes
18 sprague