Transcriptome-centric definitions of eVIP mutation impact calls.

Transcriptome-centric definitions of eVIP mutation impact calls.

<p>Transcriptome-centric definitions of eVIP mutation impact calls.</p>

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Bibliographic Details
Main Author:	Alexis M. Thornton (11068403) (author)
Other Authors:	Lishan Fang (10101825) (author), April Lo (11068406) (author), Maria McSharry (11068409) (author), David Haan (11068412) (author), Casey O’Brien (4671856) (author), Alice H. Berger (11068415) (author), Marios Giannakis (3564314) (author), Angela N. Brooks (11068418) (author)
Published:	2021
Subjects:	Biochemistry Medicine Microbiology Genetics Molecular Biology Physiology Cancer Infectious Diseases Virology Biological Sciences not elsewhere classified RAS RNF 43 R 117fs RNF 43 G 659fs KRAS eVIP 2 software Additional eVIP Pathways analysis expression-based variant impact phe... Western blot analysis change-of-function mutation G 659fs variants RNF 43 WT GOF eVIP 2 method GFP control cDNA gene variants RNF 43 WT function gene variant function decision tree-based algorithm eVIP 2 RNF 43 G 659fs HEK 293T cells use gene expression data pathway colon adenocarcinoma patient samples TNF BRAF missense mutations gene expression signatures
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