Supplemental Figure S1 from Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose Chemotherapy

<p>Supplemental Figure S1. Mean pharmacokinetic profiles for single agent talazoparib (BMN673 in phase I clinical trial PRP-001) versus combination therapy.</p>

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Príomhchruthaitheoir: Zev A. Wainberg (15047031) (author)
Rannpháirtithe: Arun S. Singh (15036660) (author), Gottfried E. Konecny (15047034) (author), Kelly E. McCann (15047037) (author), J. Randolph Hecht (15047040) (author), Jonathan Goldman (15047043) (author), Bartosz Chmielowski (15036666) (author), Richard S. Finn (10431048) (author), Neil O'Brien (15047046) (author), Erika Von Euw (15047049) (author), Megan M. Price (15047052) (author), Diego Martinez (15047055) (author), Lisa Yonemoto (15047058) (author), Meghan Brennan (15047061) (author), John A. Glaspy (15047064) (author), Dennis J. Slamon (15047067) (author)
Foilsithe / Cruthaithe: 2025
Ábhair:
Clibeanna: Cuir clib leis
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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author Zev A. Wainberg (15047031)
author2 Arun S. Singh (15036660)
Gottfried E. Konecny (15047034)
Kelly E. McCann (15047037)
J. Randolph Hecht (15047040)
Jonathan Goldman (15047043)
Bartosz Chmielowski (15036666)
Richard S. Finn (10431048)
Neil O'Brien (15047046)
Erika Von Euw (15047049)
Megan M. Price (15047052)
Diego Martinez (15047055)
Lisa Yonemoto (15047058)
Meghan Brennan (15047061)
John A. Glaspy (15047064)
Dennis J. Slamon (15047067)
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author_facet Zev A. Wainberg (15047031)
Arun S. Singh (15036660)
Gottfried E. Konecny (15047034)
Kelly E. McCann (15047037)
J. Randolph Hecht (15047040)
Jonathan Goldman (15047043)
Bartosz Chmielowski (15036666)
Richard S. Finn (10431048)
Neil O'Brien (15047046)
Erika Von Euw (15047049)
Megan M. Price (15047052)
Diego Martinez (15047055)
Lisa Yonemoto (15047058)
Meghan Brennan (15047061)
John A. Glaspy (15047064)
Dennis J. Slamon (15047067)
author_role author
dc.creator.none.fl_str_mv Zev A. Wainberg (15047031)
Arun S. Singh (15036660)
Gottfried E. Konecny (15047034)
Kelly E. McCann (15047037)
J. Randolph Hecht (15047040)
Jonathan Goldman (15047043)
Bartosz Chmielowski (15036666)
Richard S. Finn (10431048)
Neil O'Brien (15047046)
Erika Von Euw (15047049)
Megan M. Price (15047052)
Diego Martinez (15047055)
Lisa Yonemoto (15047058)
Meghan Brennan (15047061)
John A. Glaspy (15047064)
Dennis J. Slamon (15047067)
dc.date.none.fl_str_mv 2025-11-25T12:48:39Z
dc.identifier.none.fl_str_mv 10.1158/1078-0432.30706476
dc.relation.none.fl_str_mv https://figshare.com/articles/figure/Supplemental_Figure_S1_from_Preclinical_and_Clinical_Trial_Results_Using_Talazoparib_and_Low-Dose_Chemotherapy/30706476
dc.rights.none.fl_str_mv CC BY
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Cancer
Therapeutic Research and Development
Clinical Research and Trials
Methods and Technology
Clinical Trial Results
Phase I clinical trials
Drug Targets
Oncoprotein & tumor suppressor drug targets
Preclinical Models
In vitro models of cancer
dc.title.none.fl_str_mv Supplemental Figure S1 from Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose Chemotherapy
dc.type.none.fl_str_mv Image
Figure
info:eu-repo/semantics/publishedVersion
image
description <p>Supplemental Figure S1. Mean pharmacokinetic profiles for single agent talazoparib (BMN673 in phase I clinical trial PRP-001) versus combination therapy.</p>
eu_rights_str_mv openAccess
id Manara_bb89e07ab7f438c59d32b855b3b0c248
identifier_str_mv 10.1158/1078-0432.30706476
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/30706476
publishDate 2025
repository.mail.fl_str_mv
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rights_invalid_str_mv CC BY
spelling Supplemental Figure S1 from Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose ChemotherapyZev A. Wainberg (15047031)Arun S. Singh (15036660)Gottfried E. Konecny (15047034)Kelly E. McCann (15047037)J. Randolph Hecht (15047040)Jonathan Goldman (15047043)Bartosz Chmielowski (15036666)Richard S. Finn (10431048)Neil O'Brien (15047046)Erika Von Euw (15047049)Megan M. Price (15047052)Diego Martinez (15047055)Lisa Yonemoto (15047058)Meghan Brennan (15047061)John A. Glaspy (15047064)Dennis J. Slamon (15047067)CancerTherapeutic Research and DevelopmentClinical Research and TrialsMethods and TechnologyClinical Trial ResultsPhase I clinical trialsDrug TargetsOncoprotein & tumor suppressor drug targetsPreclinical ModelsIn vitro models of cancer<p>Supplemental Figure S1. Mean pharmacokinetic profiles for single agent talazoparib (BMN673 in phase I clinical trial PRP-001) versus combination therapy.</p>2025-11-25T12:48:39ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1158/1078-0432.30706476https://figshare.com/articles/figure/Supplemental_Figure_S1_from_Preclinical_and_Clinical_Trial_Results_Using_Talazoparib_and_Low-Dose_Chemotherapy/30706476CC BYinfo:eu-repo/semantics/openAccessoai:figshare.com:article/307064762025-11-25T12:48:39Z
spellingShingle Supplemental Figure S1 from Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose Chemotherapy
Zev A. Wainberg (15047031)
Cancer
Therapeutic Research and Development
Clinical Research and Trials
Methods and Technology
Clinical Trial Results
Phase I clinical trials
Drug Targets
Oncoprotein & tumor suppressor drug targets
Preclinical Models
In vitro models of cancer
status_str publishedVersion
title Supplemental Figure S1 from Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose Chemotherapy
title_full Supplemental Figure S1 from Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose Chemotherapy
title_fullStr Supplemental Figure S1 from Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose Chemotherapy
title_full_unstemmed Supplemental Figure S1 from Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose Chemotherapy
title_short Supplemental Figure S1 from Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose Chemotherapy
title_sort Supplemental Figure S1 from Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose Chemotherapy
topic Cancer
Therapeutic Research and Development
Clinical Research and Trials
Methods and Technology
Clinical Trial Results
Phase I clinical trials
Drug Targets
Oncoprotein & tumor suppressor drug targets
Preclinical Models
In vitro models of cancer