miRNA 221 improved left ventricular contractile function in MIRI mice.

<p>(A) Representative M-mode left ventricular echocardiographic images of mice. (B-E) In vivo assessment of heart function by echocardiography. The left ventricular ejection fraction (LVEF; B), left ventricular shortening fraction (LVFS; C), diastolic left ventricular internal diameter (LVIDd;...

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Bibliographic Details
Main Author:	Hongyu Li (1332669) (author)
Other Authors:	Jimiao Qiu (20642682) (author), Chang Liu (35901) (author), Guobing Yu (20642685) (author), Danyu Wu (20642688) (author), Yichun Chu (2644972) (author), Kai Wang (21246) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Cell Biology Genetics Molecular Biology Developmental Biology Cancer Chemical Sciences not elsewhere classified western blot assessed caspase 3 proteins targeted myocardial injection ser16 ), p alleviate myocardial injury mouse myocardial ischemia total calcium levels myocardium calcium concentration miri mouse model mirna 221 level phospholamban </ p thr17 ), serca2 thr17 ), myocardial ischemia myocardial injury mouse heart calcium levels mirna 221 xlink "> targeting interaction structural integrity significantly reduced significant enhancement significant decrease scr groups reagent kits quantitative rt positive cells pcr analysis masson staining marked decrease marked alleviation increased markedly evaluated using cyt c
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miRNA 221 improved left ventricular contractile function in MIRI mice.

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