Early Steps of Individual Multireceptor Viral Interactions Dissected by High-Density, Multicolor Quantum Dot Mapping in Living Cells

Viral capture and entry to target cells are the first crucial steps that ultimately lead to viral infection. Understanding these events is essential toward the design and development of suitable antiviral drugs and/or vaccines. Viral capture involves dynamic interactions of the virus with specific r...

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Bibliographic Details
Main Author:	Nicolas Mateos (6481928) (author)
Other Authors:	Enric Gutierrez-Martinez (19830353) (author), Jessica Angulo-Capel (19830356) (author), Irene Carlon-Andres (8479437) (author), Sergi Padilla-Parra (166100) (author), Maria F. Garcia-Parajo (10022968) (author), Juan A. Torreno-Pina (19830359) (author)
Published:	2024
Subjects:	Medicine Neuroscience Biotechnology Ecology Immunology Mental Health Infectious Diseases Virology Chemical Sciences not elsewhere classified technical challenges associated suitable antiviral drugs coordinated spatiotemporal diffusion concerted diffusion impacts specific cellular components co -) receptors first crucial steps potential viral infectivity multireceptor viral interactions three different viral single virus tracking three different specific receptors time interactions initial steps host interactions early steps viral processes viral infection ultimately lead target cells systematic analysis single level residence time relevant spatial quantitative tools powerful approach multimolecular systems molecule localizations molecule level methodology offers living cells last years largely impeded individual virus healthy donors essential toward easily implemented direct visualization cumulated single capture real approach revealed
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Early Steps of Individual Multireceptor Viral Interactions Dissected by High-Density, Multicolor Quantum Dot Mapping in Living Cells

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