The adaptive immune responses are limited to the site of injection.

<p>WT mice were injected in one spot with PBS or mRNA-LNP coding for PR8 HA. Fourteen days later the lymph nodes were harvested from the non-immunized side (nis) or the immunized side (is) and the % of GC B cells determined using flow cytometer. One experiment with multiple mice is shown.</...

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Bibliographic Details
Main Author:	Sonia Ndeupen (11993937) (author)
Other Authors:	Aurélie Bouteau (6740024) (author), Christopher Herbst (6437990) (author), Zhen Qin (411748) (author), Sonya Jacobsen (11993940) (author), Nicholas E. Powers (8785298) (author), Zachary Hutchins (11993943) (author), Drishya Kurup (3842464) (author), Leila Zabihi Diba (10451835) (author), Megan Watson (11993946) (author), Holly Ramage (10049353) (author), Botond Z. Igyártó (6740036) (author)
Published:	2022
Subjects:	Microbiology Cell Biology Molecular Biology Physiology Evolutionary Biology Immunology Developmental Biology Cancer Mental Health Hematology Infectious Diseases Biological Sciences not elsewhere classified mice remained protected protective immune responses humoral immune responses ionizable lipid component highly inflammatory due specific tfh cell lnps &# 8217 specific tfh cells antibody responses lipid nanoparticles inflammatory property xlink "> unlike neutrophils susceptibility towards significant decrease recently showed pr8 ha observed defects lethal challenge langerhans cells follicular helper combined deletion bring evidence
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The adaptive immune responses are limited to the site of injection.

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