Comparison of SPRED and GAB isoform sequences and AlphaFold docking.
<p>A-B. Conservation of DDVF (purple) motif across all three SPRED (<b>A</b>) and GAB (<b>B</b>) proteins. <b>C.</b> AlphaFold-multimer docks DDVF-like motifs from SPRED2 (green), GAB3 (red), FGFR1-4 (blue), and CNKSR2 (purple) in the RSK KAKLGM docking site...
محفوظ في:
| المؤلف الرئيسي: | |
|---|---|
| مؤلفون آخرون: | , , , |
| منشور في: |
2025
|
| الموضوعات: | |
| الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|
| الملخص: | <p>A-B. Conservation of DDVF (purple) motif across all three SPRED (<b>A</b>) and GAB (<b>B</b>) proteins. <b>C.</b> AlphaFold-multimer docks DDVF-like motifs from SPRED2 (green), GAB3 (red), FGFR1-4 (blue), and CNKSR2 (purple) in the RSK KAKLGM docking site. The predicted structures superimpose with that of the crystal structure of ORF45 DDVF (orange) bound to RSK2 (PDB 7OPO).</p> <p>(TIF)</p> |
|---|