HippoUnit test error scores show the validity of the CA1 pyramidal cell model.

HippoUnit test error scores show the validity of the CA1 pyramidal cell model.

<p>Error scores from HippoUnit test suite for 1. somatic spiking features, 2. depolarisation block, 3. back- propagating action potentials (bAPs), 4. attenuation of EPSPs, 5. nonlinear synaptic integration in oblique branches. Red line represents the acceptability threshold of two standard dev...

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Bibliographic Details
Main Author: Nicholas Hananeia (22683665) (author)
Other Authors: Christian Ebner (1276467) (author), Christos Galanis (15210328) (author), Hermann Cuntz (32618) (author), Alexander Opitz (295799) (author), Andreas Vlachos (47497) (author), Peter Jedlicka (179938) (author)
Published: 2025
Subjects:
Medicine
Cell Biology
Neuroscience
Physiology
Space Science
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
results :</ b
previous experimental studies
objective :</ b
methods :</ b
like cellular effects
conclusion :</ b
background :</ b
strongly distance dependent
scale modeling tools
repetitive magnetic stimulation
biophysical neuronal models
1 hz protocols
successfully modelled plasticity
induced synaptic plasticity
dependent plasticity model
plasticity model
dependent spatio
scale modelling
burst stimulation
5 hz
plasticity amplitude
distal plasticity
term potentiation
term changes
temporal resolution
temporal changes
rms ).
previously established
parameter screening
neurons stimulated
neuronal dendrites
modelling framework
mechanisms behind
low sensitivity
high spatio
fully understood
detailed prediction
dendritic spikes
comprehensive module
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Summary:<p>Error scores from HippoUnit test suite for 1. somatic spiking features, 2. depolarisation block, 3. back- propagating action potentials (bAPs), 4. attenuation of EPSPs, 5. nonlinear synaptic integration in oblique branches. Red line represents the acceptability threshold of two standard deviations. The model performed within two standard deviations of the experimental data and was considered acceptable.</p> <p>(TIFF)</p>

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