Figure S1 from Membranous NECTIN-4 Expression Frequently Decreases during Metastatic Spread of Urothelial Carcinoma and Is Associated with Enfortumab Vedotin Resistance

Figure S1 from Membranous NECTIN-4 Expression Frequently Decreases during Metastatic Spread of Urothelial Carcinoma and Is Associated with Enfortumab Vedotin Resistance

<p>Supplementary Figure 1. Expression of membranous NECTIN-4 in UC histology subtypes in PRIM (A) and MET (B). (C) depicts differential NECTIN-4 expression during metastatic spread. Intergroup comparison was calculated by non-parametric Kruskal-Wallis test.</p>

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Bibliografski detalji
Glavni autor: Niklas Klümper (15048887) (author)
Daljnji autori: Damian J. Ralser (15048890) (author), Jörg Ellinger (15048893) (author), Florian Roghmann (15048896) (author), Julia Albrecht (15048899) (author), Eduard Below (15048902) (author), Abdullah Alajati (15048905) (author), Danijel Sikic (15048908) (author), Johannes Breyer (15048911) (author), Christian Bolenz (15048914) (author), Friedemann Zengerling (15048917) (author), Philipp Erben (15048920) (author), Kristina Schwamborn (15048923) (author), Ralph M. Wirtz (15048926) (author), Thomas Horn (15048929) (author), Dora Nagy (15048932) (author), Marieta Toma (15048935) (author), Glen Kristiansen (15048938) (author), Thomas Büttner (15048941) (author), Oliver Hahn (15048944) (author), Viktor Grünwald (15048947) (author), Christopher Darr (15048950) (author), Eva Erne (15048953) (author), Steffen Rausch (15048956) (author), Jens Bedke (15048959) (author), Katrin Schlack (15048962) (author), Mahmoud Abbas (15048965) (author), Stefanie Zschäbitz (15048968) (author), Constantin Schwab (15048971) (author), Alexander Mustea (15048974) (author), Patrick Adam (15048977) (author), Andreas Manseck (15048980) (author), Bernd Wullich (15048983) (author), Manuel Ritter (15048986) (author), Arndt Hartmann (15048549) (author), Jürgen Gschwend (15048989) (author), Wilko Weichert (15048992) (author), Franziska Erlmeier (15048995) (author), Michael Hölzel (15048998) (author), Markus Eckstein (14949481) (author)
Izdano: 2025
Teme:
Cancer
Tumor Biology
Therapeutic Research and Development
Clinical Research and Trials
Biological Agents & Therapies
Antibody-drug conjugates
Drug Resistance
Clinical drug resistance
Drug Targets
Cell surface receptor drug targets
Genitourinary Cancers
Bladder cancer
Precision Medicine
Progression, Invasion & Metastasis
Tumor progression
Translational Research
Tumor Heterogeneity
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Opis
Sažetak:<p>Supplementary Figure 1. Expression of membranous NECTIN-4 in UC histology subtypes in PRIM (A) and MET (B). (C) depicts differential NECTIN-4 expression during metastatic spread. Intergroup comparison was calculated by non-parametric Kruskal-Wallis test.</p>

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