Risk Groups Immune Infiltration Analysis by ssGSEA Algorithm.

<p>A. Comparison of groupings of immune cells in the COAD group in low- and high-risk groups in the colon adenocarcinoma dataset (TCGA-COAD). B-C. Correlation bubble plots of immune cell infiltration abundance and key genes in the Low Risk (B) and High Risk (C) groups of COAD. TCGA, The Cancer...

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Main Author: Yongling Wang (13261656) (author)
Other Authors: Zan Yuan (15253045) (author), Yi Lao (430082) (author), Jiangtao He (2477872) (author), Shufen Mo (21743543) (author), Kangbiao Chen (20400917) (author), Yanyan Ye (2993613) (author), Lu Huang (211625) (author)
Published: 2025
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Summary:<p>A. Comparison of groupings of immune cells in the COAD group in low- and high-risk groups in the colon adenocarcinoma dataset (TCGA-COAD). B-C. Correlation bubble plots of immune cell infiltration abundance and key genes in the Low Risk (B) and High Risk (C) groups of COAD. TCGA, The Cancer Genome Atlas; COAD, Colon Adenocarcinoma; ssGSEA, Single-Sample Gene-Set Enrichment Analysis. ns stands for <i>P</i> ≥ 0.05, not statistically significant; * represents <i>P</i> < 0.05, statistically significant; ** represents <i>P</i> < 0.01, highly statistically significant; and *** represents <i>P</i> < 0.001, highly statistically significant. The absolute value of the correlation coefficient (r value) ranged from 0.5 to 0.8, indicating a moderate correlation. The light blue is for the low-risk groups, and the light red is for the high-risk groups in the group comparison. In the correlation bubble plot, light red indicates a positive correlation, and light blue indicates a negative correlation. The depth of the color represents the strength of the correlation.</p>