Figure 6 from Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival

Figure 6 from Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival

<p>ATF4 translation and protein level respond to nutrient level and are regulated by autophagy. <b>A,</b> FCs of mean fluorescence intensity (MFI) of the GFP reporter expressed from the ATF4-5′UTR-GFP translation reporter in Karpas 422 cells containing control or SIRT3 shRNAs under...

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Autore principale: Meng Li (79487) (author)
Altri autori: Matthew R. Teater (15129060) (author), Jun Young Hong (6588914) (author), Noel R. Park (15129063) (author), Cihangir Duy (15112006) (author), Hao Shen (195461) (author), Ling Wang (56577) (author), Zhengming Chen (385056) (author), Leandro Cerchietti (15091552) (author), Shawn M. Davidson (14911596) (author), Hening Lin (1306563) (author), Ari M. Melnick (15110132) (author)
Pubblicazione: 2025
Soggetti:
Cancer
Molecular and Cellular Biology
Cellular Stress Responses
Gene Regulation
Posttranscriptional and translational control
Hematological Cancers
Lymphomas
Metabolism
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